Not commonly used in humans; primarily veterinary. Historically, Coyden.
Generic Name
Clopidol
Manufacturer
Various generic manufacturers (e.g., formerly Dow Chemical)
Country
Global
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Description
Overview of the medicine
Clopidol is an anticoccidial agent primarily used in poultry to prevent and treat coccidiosis, a parasitic disease caused by Eimeria species. It is a pyridine derivative that interferes with the early developmental stages of coccidia.
Uses & Indications
Dosage
Adults
Not applicable for human adults.
Elderly
Not applicable for human elderly.
Renal_impairment
Not applicable for human use.
How to Take
Administered orally, mixed thoroughly in feed or dissolved in drinking water for poultry. Dosage typically ranges from 125-250 ppm in feed, depending on the animal species and specific formulation.
Mechanism of Action
Clopidol acts by inhibiting the development of coccidia sporozoites and merozoites in the host's intestinal cells, specifically by interfering with nucleic acid synthesis during the early asexual stages of the parasitic life cycle.
Pharmacokinetics
Onset
Not specified, but effective against early stages of infection.
Excretion
Mainly excreted in urine and feces as metabolites and unchanged drug.
Half life
Relatively short, varying with species and dose.
Absorption
Well absorbed orally in poultry, distributed rapidly.
Metabolism
Primarily metabolized in the liver.
Side Effects
Contraindications
- •Do not administer to laying hens producing eggs for human consumption (due to residue concerns)
- •Animals with known hypersensitivity to clopidol
Drug Interactions
Other Anticoccidials
Generally safe in combination with other common feed additives and veterinary drugs. Avoid simultaneous use with other anticoccidials that might have antagonistic effects or excessive toxicity.
Storage
Store in a cool, dry place, protected from light and moisture. Keep out of reach of children and animals.
Overdose
High doses can lead to toxicity, including reduced feed intake, weight loss, and neurological signs in susceptible animals. Symptomatic and supportive treatment.
Pregnancy & Lactation
In poultry, generally considered safe for breeder hens, but withdrawal periods apply for laying hens whose eggs are for human consumption.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years for premixes when stored correctly.
Availability
Veterinary pharmacies, agricultural supply stores
Approval Status
Approved for veterinary use (e.g., by FDA-CVM for poultry)
Patent Status
Patent expired
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Global Brand Names
International brand names for this medicine
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