Novacin
Generic Name
Ciprofloxacin
Manufacturer
Beximco Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| novacin 500 mg tablet | ৳ 14.00 | N/A |
Description
Overview of the medicine
Novacin is a fluoroquinolone antibiotic used to treat a wide range of bacterial infections including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and certain sexually transmitted diseases.
Uses & Indications
Dosage
Adults
250-750 mg orally twice daily, depending on the severity and type of infection.
Elderly
No specific dose adjustment for elderly patients based on age alone, but renal function should be monitored.
Renal_impairment
Dose reduction required for patients with creatinine clearance less than 50 mL/min.
How to Take
Take orally with a glass of water, with or without food. Avoid taking with dairy products or calcium-fortified juices.
Mechanism of Action
Inhibits bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication, transcription, repair, and recombination, leading to bacterial cell death.
Pharmacokinetics
Onset
Within 1-2 hours.
Excretion
Primarily excreted unchanged in the urine (50-70%) and to a lesser extent via feces (15-20%).
Half life
Approximately 3-5 hours.
Absorption
Rapid and well-absorbed from the gastrointestinal tract; bioavailability is approximately 70-80%.
Metabolism
Partially metabolized in the liver to four active metabolites, but the parent drug accounts for the majority of the activity.
Side Effects
Contraindications
- Hypersensitivity to ciprofloxacin or any other fluoroquinolone
- History of tendinitis or tendon rupture associated with fluoroquinolone use
- Concurrent use with Tizanidine
Drug Interactions
NSAIDs
Increased risk of CNS stimulation and convulsions.
Warfarin
May enhance anticoagulant effect.
Tizanidine
Increased risk of hypotension and somnolence.
Theophylline
Increased plasma levels of Theophylline, leading to toxicity.
Antacids (aluminum, magnesium, calcium)
Reduce ciprofloxacin absorption.
Storage
Store below 30°C, protect from light and moisture. Keep out of reach of children.
Overdose
No specific antidote. In case of acute overdose, gastric emptying by induced emesis or gastric lavage, followed by supportive care and hydration.
Pregnancy & Lactation
Not recommended during pregnancy unless essential, as animal studies show adverse effects. Excreted in breast milk and may cause joint problems in infants; use with caution.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
3 years from manufacturing date
Availability
Pharmacies, hospitals
Approval Status
Approved by DGDA
Patent Status
Expired
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have established the efficacy and safety of Ciprofloxacin for various bacterial infections.
Lab Monitoring
- Renal function tests
- Liver function tests
- Complete Blood Count (CBC)
- INR (for patients on Warfarin)
Doctor Notes
- Advise patients to complete the entire course of therapy to prevent antibiotic resistance.
- Counsel patients on potential severe side effects like tendinitis and peripheral neuropathy, and to seek immediate medical attention if they occur.
Patient Guidelines
- Complete the full course of medication, even if symptoms improve.
- Stay well-hydrated while taking this medicine.
- Avoid prolonged sun exposure and use sunscreen.
- Report any unusual pain, swelling, or tenderness in joints or tendons immediately.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness or affect vision; avoid driving or operating machinery until you know how Novacin affects you.
Lifestyle Advice
- Maintain good hygiene to prevent reinfection.
- Follow a balanced diet and stay active.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.