Novophane DS Shampoo
Generic Name
Zinc Pyrithione + Piroctone Olamine + Salicylic Acid
Manufacturer
ACM Laboratoire Dermatologique
Country
France
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Description
Overview of the medicine
Novophane DS is a specialized anti-dandruff shampoo formulated to treat severe dandruff, seborrheic dermatitis, and itchy, flaky scalp conditions. It typically contains antifungal agents like Zinc Pyrithione and Piroctone Olamine, and a keratolytic agent like Salicylic Acid to help eliminate flakes and soothe the scalp.
Uses & Indications
Dosage
Adults
Apply 2-3 times a week for 2-4 weeks, then once a week for maintenance. Lather, leave on for 5 minutes, then rinse thoroughly.
Elderly
Same as adult dosage.
Renal_impairment
No specific adjustment needed as it is a topical product with minimal systemic absorption.
How to Take
External use only. Apply to wet hair, lather, massage into the scalp, leave on for 5 minutes, then rinse thoroughly. Avoid contact with eyes.
Mechanism of Action
Zinc Pyrithione and Piroctone Olamine exert antifungal activity against Malassezia yeast, which is implicated in dandruff and seborrheic dermatitis. Salicylic Acid acts as a keratolytic, helping to shed dead skin cells and reduce scaling. The combination helps to normalize cell turnover and reduce inflammation.
Pharmacokinetics
Onset
Relief from itching and flaking can be noticed within a few applications.
Excretion
Rinsed off with water. Any minimally absorbed amounts would be metabolized and excreted via normal routes.
Half life
Not applicable for topical, locally acting ingredients.
Absorption
Minimal systemic absorption through the scalp. Primarily local action.
Metabolism
Minimal systemic metabolism due to negligible absorption.
Side Effects
Contraindications
- Hypersensitivity to any of the ingredients
- Broken or irritated skin on the scalp
Drug Interactions
Other topical scalp treatments
Avoid using with other strong scalp treatments without medical advice due to potential for increased irritation or altered efficacy.
Storage
Store below 25°C in a dry place. Do not freeze. Keep away from direct sunlight.
Overdose
Accidental ingestion: Contact a poison control center immediately. Topical overdose: Excessive use may lead to skin irritation. Rinse thoroughly with water.
Pregnancy & Lactation
Consult a healthcare professional before use during pregnancy or lactation. While systemic absorption is minimal, caution is advised.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 3 years from manufacturing date (unopened). 12 months after opening.
Availability
Pharmacies, drugstores, online retailers
Approval Status
Regulated as a cosmetic product; adheres to EU cosmetic regulations and local import standards.
Patent Status
Proprietary formulation, brand name registered; active ingredients are off-patent.
Clinical Trials
Studies support the efficacy of Zinc Pyrithione, Piroctone Olamine, and Salicylic Acid in treating dandruff and seborrheic dermatitis.
Lab Monitoring
- Not typically required for topical shampoo use.
Doctor Notes
- Advise patients on proper application technique.
- Emphasize consistency for optimal results.
- Counsel on recognizing signs of irritation or allergic reaction.
Patient Guidelines
- For external use only.
- Avoid contact with eyes; if contact occurs, rinse thoroughly with water.
- If irritation persists or worsens, discontinue use and consult a doctor.
- Keep out of reach of children.
Missed Dose Advice
If a dose is missed, continue with the next scheduled application. Do not apply extra to compensate.
Driving Precautions
No known effects on ability to drive or operate machinery.
Lifestyle Advice
- Maintain good scalp hygiene.
- Avoid harsh hair products and excessive heat styling.
- Manage stress, as it can worsen scalp conditions.
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Global Brand Names
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