o3
Generic Name
Omega-3 Fatty Acids (EPA/DHA) 1000 mg Capsule
Manufacturer
Reputable Pharmaceutical Company
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| o3 1000 mg capsule | ৳ 15.00 | ৳ 75.00 |
Description
Overview of the medicine
o3-1000-mg-capsule contains Omega-3 fatty acids, primarily Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA), derived from fish oil. It is used as a dietary supplement to support cardiovascular health, brain function, and overall well-being. It may also be used as an adjunctive therapy for hypertriglyceridemia.
Uses & Indications
Dosage
Adults
For hypertriglyceridemia: 2-4 capsules (2-4 g) daily, taken as a single dose or two divided doses with meals. For general health: 1 capsule (1 g) daily with a meal.
Elderly
No specific dose adjustment is generally required, but caution is advised in patients with bleeding risk.
Renal_impairment
No specific dose adjustment is currently recommended.
How to Take
Swallow capsules whole with water, preferably with meals to enhance absorption and reduce gastrointestinal upset.
Mechanism of Action
Omega-3 fatty acids exert their effects by modulating lipid metabolism, reducing inflammation, and influencing cell membrane fluidity. They primarily lower triglyceride levels by inhibiting VLDL-TG synthesis in the liver and increasing fatty acid oxidation. EPA and DHA also have anti-inflammatory and anti-arrhythmic properties.
Pharmacokinetics
Onset
Clinical effects on triglycerides may be observed within weeks, but full therapeutic effect can take several months.
Excretion
Excreted primarily through respiration as carbon dioxide and through feces; some are incorporated into tissues.
Half life
Variable, typically ranging from 2-3 days for EPA and DHA components.
Absorption
Well absorbed from the gastrointestinal tract, primarily in the small intestine. Absorption is enhanced when taken with a fatty meal.
Metabolism
Metabolized in the liver via beta-oxidation, similar to other fatty acids, and incorporated into cellular phospholipids.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation or to fish/shellfish
- Patients with known bleeding disorders or those taking anticoagulants (use with caution)
Drug Interactions
Fibrates
Concomitant use with fibrates may result in additive effects on lipid lowering.
Anticoagulants/Antiplatelet drugs
May increase the risk of bleeding. Monitor INR for warfarin users.
Storage
Store below 30°C in a dry place, away from direct sunlight. Keep out of reach of children.
Overdose
Symptoms of overdose may include increased risk of bleeding, nausea, diarrhea, or abdominal discomfort. Treatment is symptomatic and supportive. Discontinue use and seek medical attention.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit outweighs the potential risk to the fetus. It is unknown whether omega-3 fatty acids are excreted in human milk. Consult a doctor before use during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Pharmacies, supermarkets, online stores
Approval Status
Approved as a dietary supplement and/or prescription medication (depending on country and formulation)
Patent Status
Generally off-patent for basic formulations
Clinical Trials
Extensive clinical trials support the efficacy of Omega-3 fatty acids in reducing triglycerides and improving cardiovascular outcomes. Further research is ongoing regarding other potential benefits.
Lab Monitoring
- Lipid panel (triglycerides, cholesterol) should be monitored periodically, especially in patients treated for hypertriglyceridemia.
- Coagulation parameters (e.g., INR) should be monitored in patients on anticoagulants.
Doctor Notes
- Advise patients to inform about any surgical procedures planned due to potential bleeding risk.
- Counsel on the importance of lifestyle modifications alongside supplementation for optimal health benefits.
Patient Guidelines
- Take as directed by your doctor or as per label instructions.
- Do not crush or chew the capsule.
- Inform your doctor about all other medications and supplements you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
o3-1000-mg-capsule is not known to impair the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in fruits, vegetables, and lean proteins.
- Engage in regular physical activity.
- Limit intake of saturated and trans fats.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.