Ocudex
Generic Name
Moxifloxacin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ocudex 01 eye drop | ৳ 70.00 | N/A |
Description
Overview of the medicine
Ocudex 0.5% w/v Ophthalmic Solution contains Moxifloxacin, a fourth-generation fluoroquinolone antibiotic, used to treat bacterial conjunctivitis and other superficial ocular infections caused by susceptible organisms.
Uses & Indications
Dosage
Adults
Instill one drop in the affected eye(s) 3 times daily for 7 days.
Elderly
No dosage adjustment required.
Renal_impairment
No dosage adjustment required.
How to Take
For topical ophthalmic use only. Tilt head back, pull down the lower eyelid to form a pouch, instill one drop, then close eye gently. Do not touch the dropper tip to any surface.
Mechanism of Action
Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. This leads to bacterial cell death.
Pharmacokinetics
Onset
Rapid onset, typically within minutes to hours for clinical effect.
Excretion
Mainly excreted renally and hepatically if absorbed systemically; locally, it is cleared from the ocular surface.
Half life
Systemic half-life is about 11-15 hours, but ocular tissue half-life is shorter, specific data for ocular drops are limited but local effect is fast.
Absorption
Minimal systemic absorption after topical ocular administration. Therapeutic concentrations are achieved in ocular tissues.
Metabolism
Minimal systemic metabolism after ocular administration.
Side Effects
Contraindications
- Hypersensitivity to moxifloxacin or other quinolones, or to any component of the formulation.
Drug Interactions
Other ophthalmic medications
If using more than one topical ophthalmic drug, administer them at least 5 minutes apart.
Storage
Store at room temperature (below 30°C). Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Ocular overdose is unlikely to cause systemic toxicity due to minimal absorption. Flush the eye(s) with lukewarm water if an overdose occurs.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs risk. Excretion in breast milk is unknown, use with caution.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 months (unopened), 28 days after opening.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Off-patent (Generic available)
Clinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of Moxifloxacin ophthalmic solution for bacterial conjunctivitis.
Lab Monitoring
- No specific laboratory monitoring is typically required for topical ophthalmic moxifloxacin.
Doctor Notes
- Emphasize proper administration technique to patients.
- Monitor for signs of allergic reaction or superinfection.
- Advise patients not to share eye drops.
Patient Guidelines
- Complete the full course of treatment even if symptoms improve.
- Do not wear contact lenses during treatment.
- Avoid contaminating the dropper tip.
Missed Dose Advice
If a dose is missed, apply it as soon as remembered. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose.
Driving Precautions
May cause temporary blurred vision. Advise patients not to drive or operate machinery until vision is clear.
Lifestyle Advice
- Maintain good eye hygiene.
- Avoid rubbing eyes.
- Wear sunglasses outdoors if sensitive to light.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.