Ocutrex
Generic Name
Moxifloxacin 0.5% Eye Drop
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ocutrex 05 eye drop | ৳ 34.50 | N/A |
Description
Overview of the medicine
Ocutrex-05 Eye Drop contains Moxifloxacin 0.5%, a fluoroquinolone antibiotic used to treat bacterial conjunctivitis and other susceptible ocular bacterial infections.
Uses & Indications
Dosage
Adults
Instill one drop in the affected eye(s) 3 times a day for 7 days. Dosage duration may vary based on physician's assessment.
Elderly
No dosage adjustment is required for elderly patients.
Renal_impairment
No dosage adjustment is required for patients with renal impairment due to minimal systemic absorption.
How to Take
For ophthalmic use only. Wash hands before and after use. Tilt head back, pull down the lower eyelid, and instill one drop into the conjunctival sac of the affected eye. Do not touch the dropper tip to the eye or any other surface to avoid contamination. If using other eye medications, wait at least 5 minutes between applications.
Mechanism of Action
Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. This leads to bactericidal activity against a wide range of susceptible bacteria.
Pharmacokinetics
Onset
Clinical improvement typically seen within a few days of starting treatment.
Excretion
Systemically absorbed moxifloxacin is primarily excreted via renal and biliary routes, but systemic excretion is negligible with ophthalmic use.
Half life
The systemic half-life is approximately 12 hours, but local ocular concentrations are maintained for effective treatment.
Absorption
Minimal systemic absorption occurs following topical ophthalmic administration. Peak plasma concentrations are very low and often below the limit of quantification.
Metabolism
Minimal systemic metabolism is expected due to very low systemic absorption from ophthalmic administration.
Side Effects
Contraindications
- Hypersensitivity to moxifloxacin, other quinolones, or any component of the formulation
- Viral and fungal eye infections (as moxifloxacin is an antibacterial)
Drug Interactions
Other ophthalmic solutions
If more than one topical ophthalmic drug is being used, allow at least 5 minutes between applications.
Storage
Store in a cool, dry place below 30°C. Protect from light. Do not freeze. Keep bottle tightly closed when not in use. Keep out of reach of children.
Overdose
Due to minimal systemic absorption, an overdose from topical ophthalmic administration is unlikely to lead to systemic toxicity. If accidentally ingested, symptomatic and supportive treatment may be considered.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution should be exercised when administered to a nursing woman. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 months from manufacturing date when unopened. Discard 28 days after first opening the bottle.
Availability
Pharmacies and hospitals
Approval Status
Approved by regulatory authorities
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Clinical trials have demonstrated the efficacy and safety of moxifloxacin ophthalmic solution in treating bacterial conjunctivitis, showing significant bacterial eradication rates and clinical cure.
Lab Monitoring
- Routine laboratory monitoring is not typically required for topical ophthalmic moxifloxacin.
Doctor Notes
- Educate patients on proper eye drop administration technique to maximize efficacy and minimize contamination.
- Advise patients that sharing eye drops can spread infection and should be avoided.
- Monitor for signs of superinfection or adverse reactions, especially with prolonged use.
Patient Guidelines
- Remove contact lenses before applying the eye drop and wait at least 15 minutes before reinserting them.
- Do not touch the dropper tip to any surface, including your eye, to prevent contamination.
- Discard the solution 28 days after opening, even if some medicine remains.
- Complete the full course of treatment as prescribed, even if symptoms improve.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
Ocutrex-05 Eye Drop may cause temporary blurred vision or other visual disturbances. If this occurs, avoid driving or operating machinery until your vision is clear.
Lifestyle Advice
- Avoid rubbing your eyes, as this can worsen irritation or infection.
- Wear sunglasses if light sensitivity occurs.
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Global Brand Names
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