Olarif
Generic Name
Olopatadine 0.1% Eye Drop
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| olarif 01 eye drop | ৳ 110.00 | N/A |
Description
Overview of the medicine
Olarif-01 Eye Drop contains Olopatadine, an antihistamine and mast cell stabilizer, used for the temporary prevention of itching of the eye due to allergic conjunctivitis.
Uses & Indications
Dosage
Adults
One drop in the affected eye(s) twice daily (every 6 to 8 hours), approximately 6 to 8 hours apart.
Elderly
No specific dosage adjustment required for elderly patients.
Renal_impairment
No specific dosage adjustment required for patients with renal impairment.
How to Take
For ocular use only. Tilt head back, pull down the lower eyelid to form a pouch. Squeeze a single drop into the pouch. Do not touch the dropper tip to the eye or any other surface.
Mechanism of Action
Olopatadine acts as a selective histamine H1-receptor antagonist and also inhibits histamine release from mast cells, thereby preventing the symptoms of allergic conjunctivitis.
Pharmacokinetics
Onset
Rapid onset, typically within minutes after administration.
Excretion
Mainly excreted in urine, with less than 1% as unchanged drug.
Half life
Approximately 3 hours in plasma following ocular administration.
Absorption
Minimal systemic absorption following ocular administration. Peak plasma concentrations are typically reached within 2 hours.
Metabolism
Primarily metabolized via oxidation, N-demethylation, and hydroxylation.
Side Effects
Contraindications
- Hypersensitivity to Olopatadine or any component of the formulation.
Drug Interactions
Contact Lenses
Remove contact lenses prior to administration and wait at least 10 minutes before reinserting.
Systemic antihistamines
May increase systemic side effects, although minimal systemic absorption is expected.
Storage
Store at room temperature (below 30°C). Protect from light. Do not freeze.
Overdose
Overdose is unlikely with ophthalmic use. If accidental ingestion occurs, seek medical advice.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. Caution should be exercised when administered to a nursing mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months (unopened). Discard 1 month after opening.
Availability
Pharmacies, Hospitals
Approval Status
Approved by FDA & DGDA
Patent Status
Generic available (original patent expired)
Clinical Trials
Extensively studied in clinical trials for its efficacy and safety in allergic conjunctivitis. Showed significant reduction in ocular itching and redness.
Lab Monitoring
- No specific lab monitoring is generally required.
Doctor Notes
- Advise patients on proper administration technique to avoid contamination.
- Remind patients to remove contact lenses before use.
Patient Guidelines
- Follow your doctor's instructions carefully.
- Do not wear contact lenses while symptoms of allergic conjunctivitis are present.
- Discard the solution one month after opening the bottle.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not apply extra drops to make up for a missed dose.
Driving Precautions
May cause temporary blurred vision or other visual disturbances. If vision is blurred, do not drive or operate machinery until vision is clear.
Lifestyle Advice
- Avoid known allergens that trigger allergic conjunctivitis.
- Maintain good ocular hygiene.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.