Onesol-Advance
Generic Name
Ethanol 70% v/v Hand Rub
Manufacturer
ACI Limited
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| onesol advance 05 70 hand rub | ৳ 40.00 | N/A |
Description
Overview of the medicine
Onesol-Advance 05-70 Hand Rub is an alcohol-based antiseptic solution designed for rapid and effective hand disinfection. It contains 70% v/v ethanol, known for its broad-spectrum antimicrobial activity against bacteria, viruses, and fungi. It is suitable for use in healthcare settings, homes, and public places to maintain hand hygiene.
Uses & Indications
Dosage
Adults
Apply 3-5 ml to clean, dry hands. Rub hands thoroughly until dry (approx. 15-30 seconds).
Elderly
Same as adults.
Renal_impairment
No specific dosage adjustment required as it's topical.
How to Take
For external use only. Apply to hands and rub until dry. Do not rinse with water.
Mechanism of Action
Ethanol denatures proteins and solubilizes lipids, effectively disrupting cell membranes and inactivating enzymes of microorganisms, leading to their death. It acts rapidly upon contact.
Pharmacokinetics
Onset
Immediate upon application and drying (within 15-30 seconds).
Excretion
Primarily evaporates from the skin surface. Trace absorbed amounts are excreted via lungs and kidneys.
Half life
Not applicable for topical antiseptic action.
Absorption
Minimal systemic absorption through intact skin. Primarily acts on the skin surface.
Metabolism
Small amounts absorbed are metabolized by alcohol dehydrogenase.
Side Effects
Contraindications
- Hypersensitivity to alcohol or any other ingredients
- Application on open wounds or damaged skin
- Use in eyes or mucous membranes
Drug Interactions
Systemic Drugs
No known systemic drug interactions due to minimal absorption. Topical interactions are unlikely.
Storage
Store in a cool, dry place below 30°C. Keep away from heat, open flames, and direct sunlight. Keep container tightly closed.
Overdose
Ingestion can lead to alcohol poisoning. For external topical application, overdose is unlikely. Excessive use may cause skin dryness or irritation.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation due to minimal systemic absorption. Consult a healthcare professional if concerned.
Side Effects
Contraindications
- Hypersensitivity to alcohol or any other ingredients
- Application on open wounds or damaged skin
- Use in eyes or mucous membranes
Drug Interactions
Systemic Drugs
No known systemic drug interactions due to minimal absorption. Topical interactions are unlikely.
Storage
Store in a cool, dry place below 30°C. Keep away from heat, open flames, and direct sunlight. Keep container tightly closed.
Overdose
Ingestion can lead to alcohol poisoning. For external topical application, overdose is unlikely. Excessive use may cause skin dryness or irritation.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation due to minimal systemic absorption. Consult a healthcare professional if concerned.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, supermarkets, healthcare facilities, online
Approval Status
Approved by relevant health authorities (e.g., DGDA, WHO)
Patent Status
Not patented for basic formulation
WHO Essential Medicine
YesClinical Trials
Ethanol-based hand rubs are well-established, and extensive clinical data support their efficacy. Specific trials for this brand typically focus on formulation efficacy and skin tolerance.
Lab Monitoring
- Not required for routine topical use.
Doctor Notes
- Emphasize correct hand rub technique for optimal efficacy.
- Advise patients on the importance of moisturizing to prevent skin dryness with frequent use.
Patient Guidelines
- For external use only.
- Keep out of reach of children.
- Flammable: Keep away from fire or flame.
- Avoid contact with eyes. In case of contact, rinse thoroughly with water.
- Do not use on broken or irritated skin.
Missed Dose Advice
Not applicable for a hand rub; use as needed for hygiene.
Driving Precautions
No specific precautions required as it's topical and does not cause systemic impairment.
Lifestyle Advice
- Maintain overall hand hygiene practices.
- Use moisturizer if skin dryness occurs with frequent use.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.