Optichlor
Generic Name
Chloramphenicol 0.5% Eye Drop
Manufacturer
Incepta Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| optichlor 05 eye drop | ৳ 34.00 | N/A |
Description
Overview of the medicine
Optichlor 0.5% Eye Drop is an antibiotic medication used to treat bacterial eye infections.
Uses & Indications
Dosage
Adults
Instill 1-2 drops into the affected eye(s) 3-4 times daily.
Elderly
Adult dosage applies, no specific adjustment needed.
Renal_impairment
No dosage adjustment required for topical ophthalmic use.
How to Take
Wash hands before use. Tilt head back, pull down the lower eyelid to create a pouch. Instill the prescribed number of drops without touching the dropper tip to the eye or any surface.
Mechanism of Action
Chloramphenicol inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing bacterial growth.
Pharmacokinetics
Onset
Rapid local effect.
Excretion
Primarily cleared from the ocular surface by tear flow.
Half life
Systemic half-life not relevant for topical ophthalmic use.
Absorption
Poor systemic absorption from topical ophthalmic administration; good penetration into ocular tissues.
Metabolism
Minimally metabolized locally in the eye.
Side Effects
Contraindications
- Hypersensitivity to chloramphenicol or any component of the formulation
- History of bone marrow depression (e.g., aplastic anemia)
Drug Interactions
Systemic Chloramphenicol
Avoid concomitant systemic chloramphenicol unless strictly necessary due to increased risk of bone marrow toxicity.
Other Ophthalmic Preparations
If using other eye drops, wait at least 5-10 minutes between applications.
Storage
Store below 25°C in a dry place, protected from light. Do not freeze.
Overdose
Overdose is unlikely with topical ophthalmic use. If accidentally ingested or excess applied, rinse the eye with water. Symptoms are generally mild.
Pregnancy & Lactation
Use with caution during pregnancy and lactation. Consult a doctor; use only if the potential benefit justifies the potential risk to the fetus or infant.
Side Effects
Contraindications
- Hypersensitivity to chloramphenicol or any component of the formulation
- History of bone marrow depression (e.g., aplastic anemia)
Drug Interactions
Systemic Chloramphenicol
Avoid concomitant systemic chloramphenicol unless strictly necessary due to increased risk of bone marrow toxicity.
Other Ophthalmic Preparations
If using other eye drops, wait at least 5-10 minutes between applications.
Storage
Store below 25°C in a dry place, protected from light. Do not freeze.
Overdose
Overdose is unlikely with topical ophthalmic use. If accidentally ingested or excess applied, rinse the eye with water. Symptoms are generally mild.
Pregnancy & Lactation
Use with caution during pregnancy and lactation. Consult a doctor; use only if the potential benefit justifies the potential risk to the fetus or infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2 years unopened. Discard 28 days after opening.
Availability
Available in pharmacies and hospitals
Approval Status
Approved
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Chloramphenicol is a well-established antibiotic with extensive clinical data demonstrating its efficacy in treating various bacterial infections, including ophthalmic ones.
Lab Monitoring
- Routine lab monitoring is not typically required for topical ophthalmic use.
Doctor Notes
- Advise patients on proper administration technique.
- Emphasize not to use for longer than 7-10 days without re-evaluation.
- Monitor for signs of superinfection or allergic reactions.
Patient Guidelines
- Wash hands thoroughly before and after applying drops.
- Avoid touching the dropper tip to prevent contamination.
- Do not wear contact lenses during treatment.
- Complete the full course of treatment as prescribed, even if symptoms improve.
- Do not share your eye drops with others.
Missed Dose Advice
If a dose is missed, apply it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
This medicine may cause temporary blurred vision immediately after application. Do not drive or operate machinery until your vision is clear.
Lifestyle Advice
- Maintain good ocular hygiene.
- Avoid rubbing eyes.
- Protect eyes from dust and irritants.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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