Oralyte
Generic Name
Oral Rehydration Salt (ORS) Powder
Manufacturer
Local Manufacturer
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| oralyte 1025 gm powder | ৳ 6.00 | N/A |
Description
Overview of the medicine
Oralyte 1025 gm powder is an Oral Rehydration Salt (ORS) formulation used to prevent and treat dehydration caused by acute diarrhea, cholera, or vomiting. It helps replenish lost body fluids and electrolytes.
Uses & Indications
Dosage
Adults
The amount of ORS needed depends on the degree of dehydration. For mild to moderate dehydration, adults should drink 1-2 liters (5-10 sachets equivalent) over 4-6 hours, then continue to drink after each loose stool (e.g., 200 ml).
Elderly
Same as adults, adjusting according to tolerance and hydration status.
Renal_impairment
Use with caution in patients with severe renal impairment due to the risk of electrolyte imbalance. Consult a physician.
How to Take
Dissolve the entire 1025 gm powder in 50 liters of clean drinking water, or dissolve appropriate smaller portions (e.g., 20.5 gm in 1 liter). Drink the solution frequently in small amounts. Do not boil the solution after preparation. Use within 12 hours if kept at room temperature, or 24 hours if refrigerated.
Mechanism of Action
Oralyte works by replacing water and electrolytes (sodium, potassium, chloride, citrate) lost from the body during dehydration. The glucose component facilitates the absorption of sodium and water across the intestinal wall, thereby restoring fluid and electrolyte balance.
Pharmacokinetics
Onset
Rapid onset of rehydration, typically within minutes to hours depending on the severity of dehydration and intake.
Excretion
Excess electrolytes are primarily excreted via the kidneys, maintaining homeostatic balance. Water is excreted via kidneys, skin, and lungs.
Half life
Not applicable in the traditional sense for electrolytes; they are continuously utilized and regulated.
Absorption
Rapid absorption of water and electrolytes (sodium, potassium, chloride, citrate) from the gastrointestinal tract, facilitated by glucose.
Metabolism
Glucose is metabolized as an energy source. Electrolytes are primarily involved in maintaining physiological balance rather than undergoing extensive metabolism.
Side Effects
Contraindications
- Intestinal obstruction
- Paralytic ileus
- Severe vomiting preventing oral intake
- Glucose malabsorption (rare)
- Severe dehydration requiring intravenous fluids
Drug Interactions
Diuretics
May alter electrolyte balance; use with caution.
Storage
Store below 30°C in a dry place, protected from moisture and direct sunlight. Keep out of reach of children.
Overdose
Overdose is unlikely with correct preparation and administration. In rare cases of incorrect preparation (too concentrated) or in patients with severe renal impairment, electrolyte imbalances (e.g., hypernatremia, hyperkalemia) may occur. Treatment involves correcting the electrolyte imbalance and providing supportive care.
Pregnancy & Lactation
Oralyte is safe to use during pregnancy and lactation. Dehydration during these periods should be promptly treated.
Side Effects
Contraindications
- Intestinal obstruction
- Paralytic ileus
- Severe vomiting preventing oral intake
- Glucose malabsorption (rare)
- Severe dehydration requiring intravenous fluids
Drug Interactions
Diuretics
May alter electrolyte balance; use with caution.
Storage
Store below 30°C in a dry place, protected from moisture and direct sunlight. Keep out of reach of children.
Overdose
Overdose is unlikely with correct preparation and administration. In rare cases of incorrect preparation (too concentrated) or in patients with severe renal impairment, electrolyte imbalances (e.g., hypernatremia, hyperkalemia) may occur. Treatment involves correcting the electrolyte imbalance and providing supportive care.
Pregnancy & Lactation
Oralyte is safe to use during pregnancy and lactation. Dehydration during these periods should be promptly treated.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years from manufacturing date
Availability
Pharmacies, hospitals, health centers
Approval Status
Approved by national drug regulatory authorities (e.g., DGDA)
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
The efficacy and safety of Oral Rehydration Salts (ORS) are well-established through extensive clinical research and are recognized globally as a cornerstone of dehydration treatment. Specific clinical trials for 'Oralyte-1025-gm-powder' are generally not conducted as it's a generic formulation following WHO standards.
Lab Monitoring
- Routine lab monitoring is not typically required for standard ORS use. In severe cases of dehydration or underlying medical conditions, electrolyte levels may be monitored.
Doctor Notes
- Emphasize the importance of correct preparation with clean water and precise measurement.
- Advise patients to continue feeding, especially breastfeeding, during ORS therapy.
- Educate on recognizing signs of worsening dehydration and when to seek immediate medical attention.
Patient Guidelines
- Always use clean, boiled, and cooled drinking water to prepare the solution.
- Carefully follow the instructions for the amount of water needed for the powder.
- Drink the solution slowly, in small sips, and frequently.
- Do not add sugar, salt, or any other ingredients to the prepared ORS solution.
- Continue feeding, especially breastfeeding, during ORS therapy.
Missed Dose Advice
ORS is taken as needed for rehydration, not on a fixed schedule. If you stop taking it and symptoms of dehydration return, resume taking it immediately. There is no concept of a 'missed dose' for ORS.
Driving Precautions
Oralyte is unlikely to affect the ability to drive or operate machinery.
Lifestyle Advice
- Practice good hygiene, including handwashing, to prevent the spread of diarrheal diseases.
- Consume safe and clean food and water.
- Seek medical attention if symptoms worsen or if dehydration persists despite ORS use.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.