Orbidon
Generic Name
Prednisolone
Manufacturer
Opsonin Pharma Limited
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| orbidon 10 mg tablet | ৳ 3.50 | ৳ 35.00 |
Description
Overview of the medicine
Orbidon 10 mg Tablet contains Prednisolone, a corticosteroid used to treat a wide range of inflammatory and autoimmune conditions.
Uses & Indications
Dosage
Adults
Initially 5-60 mg daily in single or divided doses, adjusted according to response.
Elderly
Lower doses may be required, particularly with co-morbidities.
Renal_impairment
No specific dose adjustment typically required, but monitor fluid and electrolyte balance.
How to Take
Take with food or milk to minimize gastrointestinal upset. Do not stop suddenly; taper off under medical supervision.
Mechanism of Action
Prednisolone works by reducing inflammation and suppressing the immune system. It inhibits the release of substances that cause inflammation.
Pharmacokinetics
Onset
Varies depending on route and condition, typically hours to days for full therapeutic effect.
Excretion
Excreted mainly via urine, predominantly as inactive metabolites.
Half life
Plasma half-life is 2-4 hours, biological half-life is 18-36 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations are achieved within 1-2 hours.
Metabolism
Primarily metabolized in the liver to inactive metabolites.
Side Effects
Contraindications
- Systemic fungal infections
- Hypersensitivity to prednisolone
- Live vaccines during high-dose therapy
Drug Interactions
NSAIDs
Increased risk of gastrointestinal bleeding
Diuretics
Increased potassium loss
Antidiabetics
Reduced glucose control
Phenobarbital, Phenytoin, Rifampicin
May decrease prednisolone levels
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms include fluid retention, hypertension, hyperglycemia. Management involves supportive care and gradual withdrawal.
Pregnancy & Lactation
Category C. Use only if potential benefit outweighs risk. Excreted in breast milk; caution advised.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
3 years
Availability
Pharmacies, hospitals
Approval Status
Approved
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Extensive clinical data available due to long-standing use for various inflammatory and autoimmune conditions.
Lab Monitoring
- Blood glucose
- Electrolytes (especially potassium)
- Blood pressure
- Bone density (long-term)
Doctor Notes
- Tapering crucial to prevent adrenal crisis.
- Monitor for signs of infection and metabolic disturbances.
- Consider bone protection for long-term use.
Patient Guidelines
- Do not stop suddenly
- Report any unusual side effects
- Avoid contact with sick individuals (immunosuppression)
- Carry a steroid card
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness or visual disturbances in some individuals. Exercise caution until you know how it affects you.
Lifestyle Advice
- Maintain a healthy diet
- Regular exercise (weight management, bone health)
- Avoid excessive alcohol
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.