Ostofid Plus
Generic Name
Glucosamine Sulfate & Chondroitin Sulfate
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ostofid plus 250 mg tablet | ৳ 7.00 | ৳ 70.00 |
Description
Overview of the medicine
Ostofid Plus 250 mg Tablet is a combination supplement containing Glucosamine Sulfate and Chondroitin Sulfate, used to support joint health and manage symptoms of osteoarthritis.
Uses & Indications
Dosage
Adults
Typically, 1-2 tablets daily, or as directed by a physician. Higher doses (e.g., 500mg Glucosamine, 400mg Chondroitin, 3 times daily) are also common for different formulations.
Elderly
No specific dose adjustment needed, but caution in patients with comorbidities.
Renal_impairment
Use with caution in severe renal impairment. No specific guidelines, consult a physician.
How to Take
Oral. Can be taken with or without food. To minimize GI upset, take with food.
Mechanism of Action
Glucosamine is a natural amino sugar that plays a crucial role in building cartilage, while Chondroitin sulfate is a complex carbohydrate that helps cartilage retain water, improving elasticity and cushioning. Together, they help rebuild cartilage, reduce inflammation, and improve joint function.
Pharmacokinetics
Onset
Clinical effects are typically observed after 2-4 weeks of continuous use, with full benefits taking several months.
Excretion
Glucosamine is primarily excreted renally, with some fecal excretion. Chondroitin is primarily excreted renally.
Half life
Glucosamine has a plasma half-life of 15 hours. Chondroitin's half-life is around 3 hours.
Absorption
Glucosamine has an oral bioavailability of about 25-26%, while Chondroitin's bioavailability is around 10-20%.
Metabolism
Glucosamine is primarily metabolized in the liver. Chondroitin is partially metabolized via depolymerization and desulfation.
Side Effects
Contraindications
- •Hypersensitivity to Glucosamine, Chondroitin, or any excipients
- •Shellfish allergy (if Glucosamine derived from shellfish)
Drug Interactions
Warfarin
May enhance the anticoagulant effect, increasing risk of bleeding. Monitor INR closely.
Insulin/Antidiabetic agents
Glucosamine may affect glucose metabolism. Monitor blood glucose levels in diabetic patients.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
No specific antidote. Symptomatic and supportive treatment is recommended. High doses may cause gastrointestinal upset.
Pregnancy & Lactation
Insufficient data regarding safety in pregnancy and lactation. Avoid use or consult a physician.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months
Availability
Pharmacies, drugstores
Approval Status
Approved by local drug regulatory authorities
Patent Status
Off-patent
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Global Brand Names
International brand names for this medicine
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