Ostogen-C
Generic Name
Calcium Carbonate + Ascorbic Acid
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ostogen c 1000 mg tablet | ৳ 12.00 | ৳ 168.00 |
Description
Overview of the medicine
Ostogen-C 1000 mg is a nutritional supplement containing Calcium Carbonate and Ascorbic Acid (Vitamin C). It is used to prevent and treat calcium and vitamin C deficiencies, support bone health, and boost immunity.
Uses & Indications
Dosage
Adults
1-2 tablets daily, or as directed by physician
Elderly
Same as adults, or as directed by physician
Renal_impairment
Use with caution, dose adjustment may be required based on calcium levels
How to Take
Orally, with water, preferably after meals for better absorption and to reduce gastric upset.
Mechanism of Action
Calcium is a vital mineral for maintaining strong bones and teeth, muscle function, and nerve transmission. Vitamin C aids in the absorption of calcium from the gut, is crucial for collagen formation (a major component of bone and connective tissues), and also functions as a powerful antioxidant, boosting the immune system.
Pharmacokinetics
Onset
Gradual, for deficiency correction.
Excretion
Calcium: Primarily via feces (unabsorbed) and urine. Ascorbic Acid: Primarily renal excretion.
Half life
Calcium: Complex, elemental calcium incorporated into bone. Ascorbic Acid: Approximately 10-20 days, depending on body stores.
Absorption
Calcium: Approximately 25-35% absorbed, influenced by vitamin D and dietary factors. Ascorbic Acid: Readily absorbed from the GI tract.
Metabolism
Calcium: Not metabolized; maintained by homeostatic mechanisms. Ascorbic Acid: Partially metabolized to inactive metabolites.
Side Effects
Contraindications
- Hypersensitivity to any component
- Hypercalcemia (high calcium levels)
- Severe hypercalciuria (high calcium in urine)
- Severe renal impairment
- History of kidney stones (especially with high doses)
Drug Interactions
Bisphosphonates
Reduced absorption. Take 30-60 minutes apart.
Iron supplements
Vitamin C can enhance iron absorption.
Thiazide diuretics
May increase calcium reabsorption, leading to hypercalcemia.
Tetracyclines & Fluoroquinolones
Calcium can reduce absorption. Take 2-3 hours apart.
Thyroid hormones (Levothyroxine)
Reduced absorption. Take 4 hours apart.
Storage
Store below 30°C, in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
Symptoms include nausea, vomiting, constipation, thirst, polyuria, and in severe cases, kidney stones (hypercalcemia symptoms). Treatment involves discontinuation of the supplement, hydration, and medical management of hypercalcemia.
Pregnancy & Lactation
Generally considered safe and often recommended during pregnancy and lactation to meet increased calcium and vitamin C requirements, but consult a doctor for appropriate dosage.
Side Effects
Contraindications
- Hypersensitivity to any component
- Hypercalcemia (high calcium levels)
- Severe hypercalciuria (high calcium in urine)
- Severe renal impairment
- History of kidney stones (especially with high doses)
Drug Interactions
Bisphosphonates
Reduced absorption. Take 30-60 minutes apart.
Iron supplements
Vitamin C can enhance iron absorption.
Thiazide diuretics
May increase calcium reabsorption, leading to hypercalcemia.
Tetracyclines & Fluoroquinolones
Calcium can reduce absorption. Take 2-3 hours apart.
Thyroid hormones (Levothyroxine)
Reduced absorption. Take 4 hours apart.
Storage
Store below 30°C, in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
Symptoms include nausea, vomiting, constipation, thirst, polyuria, and in severe cases, kidney stones (hypercalcemia symptoms). Treatment involves discontinuation of the supplement, hydration, and medical management of hypercalcemia.
Pregnancy & Lactation
Generally considered safe and often recommended during pregnancy and lactation to meet increased calcium and vitamin C requirements, but consult a doctor for appropriate dosage.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years (refer to package for exact date)
Availability
Pharmacies, supermarkets
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Expired/Generic
Clinical Trials
The active ingredients, Calcium Carbonate and Ascorbic Acid, have been extensively studied in numerous clinical trials for their roles in bone health and immunity. Research on specific combinations and formulations is ongoing.
Lab Monitoring
- Serum calcium levels (especially in long-term therapy or renal impairment)
- Renal function tests
- 24-hour urinary calcium (in risk of hypercalciuria)
Doctor Notes
- Advise patients on adequate dietary calcium intake alongside supplementation.
- Exercise caution in patients with renal impairment or a history of kidney stones.
- Check for potential drug interactions, especially with tetracyclines, fluoroquinolones, and thyroid hormones.
Patient Guidelines
- Take as directed by your doctor or pharmacist.
- Do not exceed the recommended dose.
- Drink plenty of water to help prevent kidney stones.
- Inform your doctor about all other medications and supplements you are taking.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double the dose.
Driving Precautions
No known effects on driving ability.
Lifestyle Advice
- Maintain a balanced diet rich in calcium and vitamin C.
- Engage in regular weight-bearing exercise for bone health.
- Ensure adequate sun exposure for Vitamin D synthesis, which aids calcium absorption.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.