otc-ds
Generic Name
Ketoconazole 2% Shampoo
Manufacturer
Healthcare Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| otc ds 2 shampoo | ৳ 1,100.00 | N/A |
Description
Overview of the medicine
A medicated shampoo containing Ketoconazole 2% used for the treatment of dandruff and seborrheic dermatitis of the scalp.
Uses & Indications
Dosage
Adults
Apply to wet hair, lather, leave on for 3-5 minutes, then rinse thoroughly. Use twice weekly for 2-4 weeks, then once weekly or as needed for maintenance.
Elderly
No specific dosage adjustment required.
Renal_impairment
No specific dosage adjustment required due to minimal systemic absorption.
How to Take
For topical use only. Wet hair thoroughly. Apply a small amount of shampoo to the scalp and gently massage to produce a rich lather. Leave on for 3-5 minutes, then rinse completely. Avoid contact with eyes.
Mechanism of Action
Ketoconazole is an azole antifungal that inhibits the biosynthesis of ergosterol, an essential component of the fungal cell membrane, leading to increased membrane permeability and leakage of cellular contents.
Pharmacokinetics
Onset
Symptomatic improvement may be noticed after 2-4 weeks of regular use.
Excretion
Mainly through feces after systemic absorption (which is minimal).
Half life
Not relevant for topical formulation due to minimal systemic absorption.
Absorption
Minimal systemic absorption after topical application to the scalp.
Metabolism
Not extensively metabolized systemically due to minimal absorption.
Side Effects
Contraindications
- •Hypersensitivity to ketoconazole or any component of the shampoo.
Drug Interactions
Corticosteroids (topical)
If corticosteroids are used, a gradual withdrawal over 2-3 weeks is recommended to prevent rebound effects.
Storage
Store below 30°C in a dry place, away from direct sunlight. Keep out of reach of children.
Overdose
Overdose is unlikely with topical application. In case of accidental ingestion, seek medical advice.
Pregnancy & Lactation
Use with caution during pregnancy and lactation. Consult your doctor before use, although systemic absorption is minimal.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from manufacturing date
Availability
Pharmacies, supermarkets, online stores
Approval Status
Approved for OTC use
Patent Status
Patent Expired
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Global Brand Names
International brand names for this medicine
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