Ovario
Generic Name
Dehydroepiandrosterone (DHEA)
Manufacturer
Hypothetical Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ovario 150 mg tablet | ৳ 50.00 | ৳ 500.00 |
Description
Overview of the medicine
Ovario 150 mg Tablet contains Dehydroepiandrosterone (DHEA), a steroid hormone produced by the adrenal glands. It serves as a precursor to androgens and estrogens. It is used to support hormonal balance, ovarian function, and may be used in specific fertility protocols.
Uses & Indications
Dosage
Adults
Typically 75-150 mg orally once daily for 6-8 weeks prior to IVF or as directed by a specialist. Ovario 150 mg is usually one tablet daily.
Elderly
Use with caution; dosage may need adjustment based on individual hormonal levels and clinical response.
Renal_impairment
No specific dose adjustment guidelines; monitor hormonal levels and clinical response.
How to Take
Take orally with water, preferably with a meal to enhance absorption. Follow doctor's instructions strictly.
Mechanism of Action
DHEA is a prohormone that is converted in peripheral tissues into more potent androgens (like testosterone) and estrogens (like estradiol). It may improve ovarian response, egg quality, and endometrial receptivity in certain fertility settings, possibly by modulating follicular microenvironment and reducing oxidative stress.
Pharmacokinetics
Onset
Hormonal effects may take weeks to months to become apparent.
Excretion
Mainly excreted in urine as glucuronide and sulfate conjugates.
Half life
Approximately 7-10 hours for DHEA, but active metabolites (DHEA-S, androgens, estrogens) have longer half-lives.
Absorption
Well absorbed orally; peak plasma levels typically achieved within 2-4 hours. Bioavailability can vary.
Metabolism
Extensively metabolized in the liver and other peripheral tissues to DHEA sulfate (DHEA-S), androstenedione, testosterone, and estrogens.
Side Effects
Contraindications
- Pregnancy and lactation (unless specifically advised by a specialist)
- Androgen-dependent cancers (e.g., prostate cancer, some breast cancers)
- History of mania or severe psychiatric disorders
- Children and adolescents
Drug Interactions
Anticoagulants
May increase bleeding risk.
Corticosteroids
DHEA can potentially reduce the effects of corticosteroids.
Hormone Replacement Therapy (HRT)
May alter effects of HRT; monitor hormone levels.
Insulin sensitizers (e.g., Metformin)
Potential for altered glucose metabolism; monitor blood sugar.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Overdose symptoms may include severe androgenic effects (acne, hair growth, voice changes) or estrogenic effects. Management is supportive and symptomatic; discontinue DHEA.
Pregnancy & Lactation
Contraindicated during pregnancy and lactation due to potential hormonal effects on the fetus/infant, unless specifically advised and monitored by a fertility specialist for specific conditions.
Side Effects
Contraindications
- Pregnancy and lactation (unless specifically advised by a specialist)
- Androgen-dependent cancers (e.g., prostate cancer, some breast cancers)
- History of mania or severe psychiatric disorders
- Children and adolescents
Drug Interactions
Anticoagulants
May increase bleeding risk.
Corticosteroids
DHEA can potentially reduce the effects of corticosteroids.
Hormone Replacement Therapy (HRT)
May alter effects of HRT; monitor hormone levels.
Insulin sensitizers (e.g., Metformin)
Potential for altered glucose metabolism; monitor blood sugar.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Overdose symptoms may include severe androgenic effects (acne, hair growth, voice changes) or estrogenic effects. Management is supportive and symptomatic; discontinue DHEA.
Pregnancy & Lactation
Contraindicated during pregnancy and lactation due to potential hormonal effects on the fetus/infant, unless specifically advised and monitored by a fertility specialist for specific conditions.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies, health stores, online retailers.
Approval Status
Available as a dietary supplement; Prescription status varies by region for drug formulations.
Patent Status
Generic available; Specific formulation patents may exist.
Clinical Trials
Numerous clinical trials are ongoing or completed investigating DHEA's role in fertility, aging, and other hormonal conditions. Efficacy for specific indications may vary.
Lab Monitoring
- Serum DHEA-S levels
- Testosterone and estradiol levels
- Liver function tests
- Lipid profile
- Blood glucose
Doctor Notes
- Counsel patients on potential androgenic side effects, especially in women.
- Emphasize the importance of regular hormone level monitoring.
- Ovario 150 mg Tablet should be used as part of a supervised fertility treatment regimen.
Patient Guidelines
- Do not exceed the prescribed dose.
- Report any unusual side effects to your doctor.
- Regular monitoring of hormone levels is important.
- This medication is part of a comprehensive treatment plan and should not be used in isolation.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Generally, Ovario 150 mg Tablet does not affect driving ability. However, if you experience dizziness or mood changes, avoid driving or operating heavy machinery.
Lifestyle Advice
- Maintain a healthy diet and regular exercise.
- Avoid smoking and excessive alcohol consumption.
- Manage stress effectively, as it can impact hormonal balance.
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