Oxydrop
Generic Name
Oxymetazoline Hydrochloride
Manufacturer
Example Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| oxydrop 005 nasal drop | ৳ 50.00 | N/A |
Description
Overview of the medicine
Oxydrop-005 Nasal Drop contains Oxymetazoline Hydrochloride, a topical decongestant used to relieve nasal congestion due to colds, sinusitis, hay fever, and other upper respiratory allergies. It works by constricting blood vessels in the nasal passages.
Uses & Indications
Dosage
Adults
Adults and children 6 years of age and over: 2-3 drops in each nostril, not more often than every 10-12 hours. Do not exceed 2 doses in 24 hours. Use for no more than 3 consecutive days.
Elderly
No specific dosage adjustment required; use as per adult dosage.
Renal_impairment
No specific dosage adjustment required for topical nasal application.
How to Take
Clear the nasal passages by gently blowing your nose before use. Tilt your head slightly backward and apply the prescribed number of drops into each nostril. Keep your head tilted for a few seconds to allow the drops to spread. Avoid touching the dropper tip to the nose to prevent contamination. Wash hands after use.
Mechanism of Action
Oxymetazoline is a direct-acting sympathomimetic amine. It stimulates alpha-adrenergic receptors in the arterioles of the nasal mucosa, producing vasoconstriction and reducing blood flow, which in turn decreases swelling and opens nasal passages.
Pharmacokinetics
Onset
Within minutes (typically 5-10 minutes).
Excretion
Excreted in urine, mainly unchanged if systemically absorbed.
Half life
Systemic half-life not precisely defined for topical use, but local effects last up to 12 hours.
Absorption
Minimal systemic absorption occurs from the nasal mucosa, but local absorption is significant for therapeutic effect.
Metabolism
Primarily metabolized in the liver if systemically absorbed.
Side Effects
Contraindications
- Hypersensitivity to oxymetazoline or any component of the formulation.
- Patients with transsphenoidal hypophysectomy or surgery exposing the dura mater.
- Patients receiving monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping such treatment.
- Narrow-angle glaucoma.
Drug Interactions
Beta-adrenergic blockers
May increase blood pressure and interact with decongestants.
Tricyclic Antidepressants (TCAs)
May potentiate the pressor effects of oxymetazoline.
Monoamine Oxidase Inhibitors (MAOIs)
Concurrent use may lead to severe hypertensive crisis. Avoid using oxymetazoline within 14 days of MAOI therapy.
Storage
Store below 30°C. Protect from light. Keep out of reach of children.
Overdose
Symptoms of overdose may include severe drowsiness, sweating, dizziness, slow heartbeat, high blood pressure, and coma. If swallowed, call emergency services immediately. Treatment is supportive.
Pregnancy & Lactation
Use during pregnancy and lactation only if clearly needed and the potential benefits outweigh the potential risks. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
3 years (unopened). Discard 28 days after opening.
Availability
Pharmacies, general stores
Approval Status
Approved (OTC)
Patent Status
Generic available
Clinical Trials
Oxymetazoline has been widely studied for its efficacy and safety as a nasal decongestant in numerous clinical trials supporting its use for various causes of nasal congestion.
Lab Monitoring
- No specific laboratory monitoring is generally required for topical nasal decongestants.
Doctor Notes
- Emphasize the importance of short-term use to prevent rhinitis medicamentosa.
- Advise caution in patients with hypertension, cardiovascular disease, hyperthyroidism, or diabetes.
- Instruct patients on proper administration technique to maximize efficacy and minimize side effects.
Patient Guidelines
- Do not use for more than 3 consecutive days to avoid rebound congestion.
- Blow your nose gently before using the drops.
- Avoid sharing the bottle to prevent the spread of infection.
- If symptoms do not improve within 3 days or worsen, consult a doctor.
Missed Dose Advice
If you miss a dose, use it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not use a double dose to make up for a missed one.
Driving Precautions
Generally, Oxydrop-005 Nasal Drop does not affect the ability to drive or operate machinery. However, if you experience dizziness or any other side effect that affects concentration, avoid these activities.
Lifestyle Advice
- Maintain good hydration by drinking plenty of fluids.
- Avoid irritants like smoke and strong perfumes which can aggravate nasal congestion.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.