Phosvita
Generic Name
P Phos
Manufacturer
Global Pharma Ltd.
Country
Bangladesh
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Description
Overview of the medicine
P Phos is a mineral supplement used to treat and prevent hypophosphatemia (low blood phosphate levels). It plays a crucial role in bone health, energy metabolism, and various cellular functions.
Uses & Indications
Dosage
Adults
Typically 250-500 mg elemental phosphorus 2-4 times daily, adjusted based on serum phosphate levels.
Elderly
Similar to adults, but with caution due to potential renal impairment.
Renal_impairment
Reduced dosage or contraindicated depending on severity, strict monitoring required.
How to Take
Take with or after meals to minimize gastrointestinal upset. Swallow tablets whole with water, do not chew.
Mechanism of Action
P Phos provides inorganic phosphate ions that directly replenish the body's phosphate stores. Phosphate is essential for the formation of ATP (adenosine triphosphate), which is the primary energy currency of cells, and for the structural integrity of bones and cell membranes.
Pharmacokinetics
Onset
Within hours for oral administration.
Excretion
Primarily renal excretion.
Half life
Not a standard single half-life for elemental phosphate; primarily excreted renally.
Absorption
Oral phosphates are generally well absorbed from the gastrointestinal tract, though absorption can vary.
Metabolism
Phosphate is not metabolized in the traditional sense; it's a mineral incorporated into biological molecules.
Side Effects
Contraindications
- Hyperphosphatemia
- Hypocalcemia
- Severe renal impairment
- Active kidney stone disease (calcium phosphate stones)
Drug Interactions
Calcium Salts
May form insoluble complexes, reducing absorption of both and increasing risk of calcium phosphate precipitation.
Corticosteroids
May increase renal excretion of phosphate.
Aluminum/Magnesium Antacids
May bind phosphate, reducing its absorption.
Storage
Store below 30°C in a dry place, away from light and moisture.
Overdose
Symptoms may include hyperphosphatemia, hypocalcemia (tetany, arrhythmias), and renal complications. Management involves calcium administration, dialysis in severe cases.
Pregnancy & Lactation
Generally considered safe when used as directed to manage phosphate imbalance. Consult a doctor.
Side Effects
Contraindications
- Hyperphosphatemia
- Hypocalcemia
- Severe renal impairment
- Active kidney stone disease (calcium phosphate stones)
Drug Interactions
Calcium Salts
May form insoluble complexes, reducing absorption of both and increasing risk of calcium phosphate precipitation.
Corticosteroids
May increase renal excretion of phosphate.
Aluminum/Magnesium Antacids
May bind phosphate, reducing its absorption.
Storage
Store below 30°C in a dry place, away from light and moisture.
Overdose
Symptoms may include hyperphosphatemia, hypocalcemia (tetany, arrhythmias), and renal complications. Management involves calcium administration, dialysis in severe cases.
Pregnancy & Lactation
Generally considered safe when used as directed to manage phosphate imbalance. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Available in pharmacies and hospitals
Approval Status
Approved by DGDA
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Extensive clinical use has established efficacy and safety for phosphate replacement.
Lab Monitoring
- Serum phosphate levels
- Serum calcium levels
- Renal function tests
Doctor Notes
- Monitor serum phosphate and calcium levels regularly.
- Adjust dose based on patient's clinical response and lab values.
Patient Guidelines
- Take exactly as prescribed.
- Do not exceed the recommended dose.
- Report any muscle cramps, weakness, or irregular heartbeats.
Missed Dose Advice
If a dose is missed, take it as soon as remembered unless it's almost time for the next dose. Do not double the dose.
Driving Precautions
No known specific precautions. P Phos is unlikely to affect driving ability.
Lifestyle Advice
- Maintain a balanced diet.
- Avoid excessive intake of calcium supplements or antacids without doctor's advice.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.