Peptofit
Generic Name
Fungal Diastase + Pepsin + Simethicone
Manufacturer
Acme Pharmaceuticals Ltd.
Country
Bangladesh
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Description
Overview of the medicine
Peptofit is a digestive aid that helps in proper digestion of food and relieves symptoms like indigestion, flatulence, bloating, and dyspepsia. It contains fungal diastase and pepsin for enzymatic breakdown of carbohydrates and proteins, and simethicone to reduce gas bubbles.
Uses & Indications
Dosage
Adults
1-2 teaspoonfuls (5-10 ml) 2-3 times daily, immediately after or during meals.
Elderly
Same as adult dosage or as directed by physician.
Renal_impairment
No specific dose adjustment required as it's not systemically absorbed. Consult physician if concerns persist.
How to Take
Take orally, directly after or during meals. Shake the bottle well before use.
Mechanism of Action
Fungal diastase breaks down complex carbohydrates into simple sugars. Pepsin breaks down proteins into smaller peptides. Simethicone acts as an anti-foaming agent, reducing the surface tension of gas bubbles in the gastrointestinal tract, allowing them to coalesce and be easily expelled.
Pharmacokinetics
Onset
Within 15-30 minutes for symptomatic relief.
Excretion
Enzymes are excreted as digested products. Simethicone is excreted unchanged in feces.
Half life
Not applicable for enzymes/simethicone as they are not systemically absorbed.
Absorption
Enzymes (Fungal Diastase, Pepsin) are proteins and are mostly digested themselves; minimal systemic absorption. Simethicone is not absorbed from the gastrointestinal tract.
Metabolism
Enzymes are digested. Simethicone is metabolically inert.
Side Effects
Contraindications
- Known hypersensitivity to any of the ingredients (fungal diastase, pepsin, simethicone).
- Acute pancreatitis or exacerbation of chronic pancreatitis.
Drug Interactions
Antacids
May slightly reduce the efficacy of enzymes, particularly if taken simultaneously. It's advisable to separate doses by at least an hour.
Storage
Store in a cool, dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Overdose is unlikely to cause severe adverse effects due to minimal systemic absorption. Management is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe, but use with caution. Consult a doctor before using during pregnancy or breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from manufacturing date.
Availability
Available in pharmacies and drugstores
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Off-patent (components are generic)
Clinical Trials
Specific clinical trials for the brand 'Peptofit' are limited; however, its individual components (fungal diastase, pepsin, simethicone) have well-established efficacy and safety profiles through numerous studies.
Lab Monitoring
- No routine lab monitoring is required for Peptofit.
Doctor Notes
- Advise patients on lifestyle modifications for dyspepsia (diet, stress management).
- Educate patients that this is a symptomatic relief and not a cure for underlying GI diseases.
- Consider further investigation if symptoms are persistent, severe, or associated with alarm features (e.g., weight loss, bleeding).
Patient Guidelines
- Take Peptofit as directed by your doctor or pharmacist.
- Do not exceed the recommended dose.
- If symptoms persist for more than 7 days, consult your doctor.
Missed Dose Advice
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Peptofit is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a healthy and balanced diet.
- Avoid foods that commonly cause indigestion or gas (e.g., fatty foods, carbonated drinks, certain vegetables).
- Eat smaller, more frequent meals.
- Practice stress management techniques.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.