Administer orally with or without food. Take the prescribed dose as directed by a physician. Liquid forms should be measured with a special spoon or device.

Cyproheptadine acts as a potent histamine H1 receptor antagonist, blocking the effects of histamine and thereby alleviating allergy symptoms. It also has serotonin antagonist properties and weak anticholinergic effects. Its appetite-stimulating effect is thought to be related to its serotonin antagonism at the hypothalamus.

• •Hypersensitivity to Cyproheptadine or similar drugs
• •Newborns or premature infants
• •Nursing mothers
• •Angle-closure glaucoma
• •Urinary retention (e.g., due to prostatic hypertrophy)
• •Stenosing peptic ulcer
• •Concomitant use of MAO inhibitors

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Do not freeze syrup.

Symptoms of overdose may include severe drowsiness, dizziness, dilated pupils, dry mouth, flushed skin, fever, hallucinations, ataxia, or seizures. Management is supportive and symptomatic, including gastric lavage or activated charcoal if recent ingestion, and maintaining respiration and circulation. Physostigmine may be considered in severe anticholinergic toxicity.

Pregnancy Category B. Studies in animals have shown no evidence of harm to the fetus, but there are no adequate and well-controlled studies in pregnant women. Use only if clearly needed. Not recommended during lactation as it may pass into breast milk and potentially harm a nursing infant or cause sedation.