Perminova
Generic Name
permin
Manufacturer
MediCare Pharma Ltd.
Country
Bangladesh
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Description
Overview of the medicine
A novel broad-spectrum antiviral agent used for treating various viral infections.
Uses & Indications
Dosage
Adults
200 mg orally twice daily for 5-7 days.
Elderly
Dose adjustment may be required based on renal function.
Renal_impairment
Reduce dose to 100 mg daily for severe impairment.
How to Take
Take with or without food. Swallow whole, do not crush.
Mechanism of Action
Permin inhibits viral RNA polymerase, preventing viral replication.
Pharmacokinetics
Onset
Within 1-2 hours.
Excretion
Mainly renal (60%) and fecal (40%).
Half life
8-12 hours.
Absorption
Rapidly absorbed after oral administration, bioavailability ~70%.
Metabolism
Primarily hepatic metabolism via CYP3A4.
Side Effects
Contraindications
- Hypersensitivity to permin
- Severe hepatic impairment
- Pregnancy
Drug Interactions
CYP3A4 inducers
May decrease permin levels.
CYP3A4 inhibitors
May increase permin levels.
Storage
Store below 30°C, protect from light and moisture.
Overdose
Symptomatic and supportive treatment. No specific antidote.
Pregnancy & Lactation
Not recommended during pregnancy and lactation due to lack of safety data.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, Hospitals
Approval Status
Approved (DGDA, FDA)
Patent Status
Patented until 2035
Clinical Trials
Phase III trials demonstrated significant reduction in viral load for influenza and dengue.
Lab Monitoring
- Liver function tests
- Renal function tests
- Viral load monitoring
Doctor Notes
- Advise patients on compliance.
- Monitor liver enzymes periodically.
Patient Guidelines
- Complete the full course of treatment even if symptoms improve.
- Report any unusual side effects.
Missed Dose Advice
Take as soon as remembered. If close to next dose, skip and continue regular schedule. Do not double dose.
Driving Precautions
May cause dizziness; avoid driving if affected.
Lifestyle Advice
- Maintain hydration.
- Avoid alcohol during treatment.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.