Polysoft PN0V40H75SUTURE
Generic Name
Polysoft PN0V40H75SUTURE USP0 (Polyglactin)
Manufacturer
Polybond India Pvt Ltd
Country
India
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Description
Overview of the medicine
Polysoft PN0V40H75SUTURE USP0 is a synthetic absorbable sterile surgical suture made from a copolymer of 90% Glycolide and 10% L-Lactide (Polyglactin 910). It is dyed violet and is known for its smooth passage through tissue, excellent knot security, and predictable absorption profile. This suture is intended for general soft tissue approximation and/or ligation where an absorbable suture is indicated.
Uses & Indications
Dosage
Adults
As required by the surgical procedure and surgeon's professional judgment.
Elderly
As required by the surgical procedure and surgeon's professional judgment; no specific age-related adjustments.
Renal_impairment
Not applicable, as systemic absorption is minimal and metabolites are naturally excreted.
How to Take
For surgical use only. Administered by trained medical professionals using aseptic technique. Do not use if package is opened or damaged.
Mechanism of Action
Polyglactin 910 sutures provide initial tensile strength to approximate tissue. This strength is gradually lost as the suture material undergoes hydrolysis in the body. The copolymer degrades into glycolic and lactic acids, which are then absorbed and metabolized.
Pharmacokinetics
Onset
Provides immediate tensile support upon surgical placement.
Excretion
Metabolized products are primarily excreted via the kidneys and lungs.
Half life
Not applicable in the pharmacological sense. Tensile strength half-life is approximately 14-21 days for 50% retention.
Absorption
Suture material is absorbed by hydrolysis. Approximately 50% of tensile strength is retained at 21 days. Complete absorption typically occurs between 56 to 70 days.
Metabolism
Hydrolysis products (glycolic acid and lactic acid) are metabolized into carbon dioxide and water.
Side Effects
Contraindications
- •Not to be used where prolonged approximation of tissue under stress is required (e.g., in cardiac or vascular prostheses).
- •Should not be used in patients with known sensitivities or allergies to polyglactin 910 or its components.
- •Not recommended for implantation in tissues that will be exposed to infection for extended periods or in critically vascularized areas where rapid absorption could compromise healing.
Drug Interactions
0
No specific drug interactions are known for polyglactin sutures.
1
Consider compatibility with other surgical materials or implants.
Storage
Store at room temperature (below 30°C), protected from moisture and direct sunlight. Do not resterilize. Keep in original packaging until use.
Overdose
Not applicable. This is a surgical device, not a drug with a typical overdose risk. Improper use or excessive tension may lead to tissue damage.
Pregnancy & Lactation
Used as indicated in surgical procedures for pregnant or lactating women. No known direct adverse effects on pregnancy or lactation from the suture material itself.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 5 years from the date of manufacture, when stored under recommended conditions.
Availability
Hospitals, Surgical Centers, Medical Supply Stores
Approval Status
Approved (Medical Device)
Patent Status
Patents Expired for Polyglactin material; Brand specific patents may exist.
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