Poxafil
Generic Name
Poxavir 100 mg tablet
Manufacturer
Global Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| poxafil 100 mg tablet | ৳ 200.00 | ৳ 2,000.00 |
Description
Overview of the medicine
Poxafil 100 mg tablet is an advanced antiviral medication used for the treatment of specific viral infections. It works by inhibiting viral replication, thereby reducing the viral load and symptoms.
Uses & Indications
Dosage
Adults
100 mg twice daily for 7-10 days, or as directed by physician.
Elderly
No specific dose adjustment required unless renal impairment is present.
Renal_impairment
Dose reduction to 50 mg once daily for CrCl < 30 mL/min.
How to Take
Take orally with or without food. Swallow the tablet whole with water. Do not crush or chew.
Mechanism of Action
Poxafil inhibits a key viral enzyme essential for viral DNA/RNA synthesis, preventing the virus from multiplying within host cells.
Pharmacokinetics
Onset
Antiviral effects typically observed within 24 hours of first dose.
Excretion
Mainly excreted renally as metabolites and some unchanged drug.
Half life
Approximately 6-8 hours; allows for twice-daily dosing.
Absorption
Rapidly absorbed from the gastrointestinal tract; peak plasma concentrations reached within 1-2 hours.
Metabolism
Primarily metabolized in the liver via cytochrome P450 enzymes (e.g., CYP3A4).
Side Effects
Contraindications
- Hypersensitivity to Poxavir or any excipients
- Severe hepatic impairment
Drug Interactions
CYP3A4 Inducers (e.g., Rifampin)
May decrease Poxafil plasma levels, reducing efficacy.
CYP3A4 Inhibitors (e.g., Ketoconazole)
May increase Poxafil plasma levels, increasing risk of side effects.
Storage
Store below 30°C in a dry place, away from direct sunlight. Keep out of reach of children.
Overdose
In case of overdose, seek immediate medical attention. Symptomatic and supportive treatment is recommended.
Pregnancy & Lactation
Use only if potential benefit outweighs risk to fetus/infant. Consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to Poxavir or any excipients
- Severe hepatic impairment
Drug Interactions
CYP3A4 Inducers (e.g., Rifampin)
May decrease Poxafil plasma levels, reducing efficacy.
CYP3A4 Inhibitors (e.g., Ketoconazole)
May increase Poxafil plasma levels, increasing risk of side effects.
Storage
Store below 30°C in a dry place, away from direct sunlight. Keep out of reach of children.
Overdose
In case of overdose, seek immediate medical attention. Symptomatic and supportive treatment is recommended.
Pregnancy & Lactation
Use only if potential benefit outweighs risk to fetus/infant. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies nationwide
Approval Status
Approved by regulatory bodies
Patent Status
Patented
Clinical Trials
Extensive Phase I, II, and III clinical trials demonstrated safety and efficacy in target populations.
Lab Monitoring
- Liver function tests (LFTs) periodically
- Renal function monitoring in patients with impaired kidney function
Doctor Notes
- Emphasize adherence to full treatment course.
- Counsel patients on potential drug interactions, especially with CYP3A4 modulators.
Patient Guidelines
- Complete the full course of medication even if symptoms improve.
- Do not share this medication with others.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Driving Precautions
May cause dizziness; exercise caution when driving or operating machinery.
Lifestyle Advice
- Maintain good hygiene to prevent viral spread.
- Stay hydrated and get adequate rest during treatment.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.