Prenovax-23
Generic Name
Respiratory Syncytial Virus (RSV) Subunit Vaccine
Manufacturer
BioGen Pharma
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| prenovax 23 25 mcg injection | ৳ 2,500.00 | N/A |
Description
Overview of the medicine
Prenovax-23 is a subunit vaccine indicated for active immunization to prevent Respiratory Syncytial Virus (RSV) lower respiratory tract disease in specific populations. It contains 25 mcg of the purified F protein of RSV, formulated as an injectable suspension.
Uses & Indications
Dosage
Adults
0.5 mL single intramuscular dose.
Elderly
0.5 mL single intramuscular dose.
Renal_impairment
No dosage adjustment required.
How to Take
Administer intramuscularly, preferably in the deltoid muscle.
Mechanism of Action
Prenovax-23 works by inducing an immune response against the Respiratory Syncytial Virus (RSV) F protein. The F protein is crucial for viral entry into host cells. By presenting a stabilized form of this protein, the vaccine stimulates the production of neutralizing antibodies and cell-mediated immunity, thereby protecting against RSV infection and disease.
Pharmacokinetics
Onset
Immunity typically develops within 2-4 weeks after vaccination.
Excretion
Not applicable for a vaccine; immune components are cleared naturally.
Half life
Not applicable to the vaccine itself; refers to antibody persistence, which varies.
Absorption
Not applicable for a vaccine; the active component is processed by antigen-presenting cells at the injection site.
Metabolism
Not applicable for a vaccine; antigenic proteins are processed by the immune system.
Side Effects
Contraindications
- Severe allergic reaction (e.g., anaphylaxis) to any component of the vaccine or to a previous dose of Prenovax-23.
- Acute severe febrile illness; postpone vaccination until recovery.
Drug Interactions
Other vaccines
Can be co-administered with other vaccines, but in different injection sites.
Immunosuppressants
May diminish the immune response to Prenovax-23.
Storage
Store refrigerated at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.
Overdose
Overdose is highly unlikely as Prenovax-23 is administered by healthcare professionals in controlled doses. In case of suspected overdose, provide symptomatic treatment.
Pregnancy & Lactation
Indicated for maternal immunization to protect infants. Consult healthcare provider for administration during lactation.
Side Effects
Contraindications
- Severe allergic reaction (e.g., anaphylaxis) to any component of the vaccine or to a previous dose of Prenovax-23.
- Acute severe febrile illness; postpone vaccination until recovery.
Drug Interactions
Other vaccines
Can be co-administered with other vaccines, but in different injection sites.
Immunosuppressants
May diminish the immune response to Prenovax-23.
Storage
Store refrigerated at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.
Overdose
Overdose is highly unlikely as Prenovax-23 is administered by healthcare professionals in controlled doses. In case of suspected overdose, provide symptomatic treatment.
Pregnancy & Lactation
Indicated for maternal immunization to protect infants. Consult healthcare provider for administration during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date when stored correctly.
Availability
Hospitals, Clinics, Vaccination Centers
Approval Status
Approved by DGDA (hypothetical)
Patent Status
Patent protected
Clinical Trials
Extensive Phase 1, 2, and 3 clinical trials demonstrated the safety and efficacy of Prenovax-23 in target populations, with primary endpoints including prevention of medically attended RSV lower respiratory tract disease.
Lab Monitoring
- No specific lab monitoring is required post-vaccination. Antibody titers may be measured for research purposes.
Doctor Notes
- Ensure proper cold chain maintenance for storage.
- Administer by intramuscular injection only.
- Educate patients on potential mild, transient side effects and when to seek medical attention.
Patient Guidelines
- Inform your doctor if you have any severe allergies or a history of Guillain-Barré Syndrome.
- Report any serious or unusual side effects to your healthcare provider immediately.
- Keep your vaccination record updated.
Missed Dose Advice
Prenovax-23 is typically a single-dose vaccine. For multi-dose regimens (if applicable), consult your healthcare provider regarding any missed doses.
Driving Precautions
Prenovax-23 is not expected to affect the ability to drive or use machines. However, if you experience fever, headache, or fatigue, avoid these activities until symptoms subside.
Lifestyle Advice
- Maintain a healthy lifestyle to support your immune system.
- Avoid strenuous activity immediately after vaccination if injection site reaction is present.
- Stay hydrated.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.