Preservin
Generic Name
preservin-100-mg-tablet
Manufacturer
MediCare Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| preservin 100 mg tablet | ৳ 5.00 | ৳ 50.00 |
Description
Overview of the medicine
Preservin 100 mg Tablet is a novel antioxidant and cell protectant designed to mitigate oxidative stress and preserve cellular integrity. It is indicated for conditions associated with cellular damage.
Uses & Indications
Dosage
Adults
100 mg once daily, preferably with a meal. Dosage may be adjusted based on clinical response.
Elderly
No specific dose adjustment required unless significant renal or hepatic impairment is present.
Renal_impairment
For mild to moderate impairment, no dose adjustment. Severe impairment: 50 mg once daily.
How to Take
Swallow the tablet whole with water. Do not crush or chew. Can be taken with or without food, but preferably with food to minimize gastric upset.
Mechanism of Action
Preservin acts by directly neutralizing reactive oxygen species (ROS) and enhancing endogenous antioxidant enzyme activity. It stabilizes cell membranes and prevents lipid peroxidation, thereby protecting cellular structures from damage.
Pharmacokinetics
Onset
Within 1-3 hours
Excretion
Mainly excreted renally (60%) and hepatically (40%) within 24 hours.
Half life
Approximately 6-8 hours
Absorption
Rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations achieved within 1-2 hours.
Metabolism
Primarily hepatic metabolism via cytochrome P450 enzymes, forming inactive metabolites.
Side Effects
Contraindications
- Hypersensitivity to the active substance or excipients
- Acute liver failure
Drug Interactions
Warfarin
May enhance anticoagulant effect, requiring closer INR monitoring.
Immunosuppressants
Potentially reduced efficacy of Preservin.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include severe gastrointestinal distress, headache, and dizziness. Treatment is symptomatic and supportive. Gastric lavage may be considered if recent ingestion.
Pregnancy & Lactation
Consult a doctor before use during pregnancy or lactation. Limited data available; use only if potential benefits outweigh risks.
Side Effects
Contraindications
- Hypersensitivity to the active substance or excipients
- Acute liver failure
Drug Interactions
Warfarin
May enhance anticoagulant effect, requiring closer INR monitoring.
Immunosuppressants
Potentially reduced efficacy of Preservin.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include severe gastrointestinal distress, headache, and dizziness. Treatment is symptomatic and supportive. Gastric lavage may be considered if recent ingestion.
Pregnancy & Lactation
Consult a doctor before use during pregnancy or lactation. Limited data available; use only if potential benefits outweigh risks.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved by regulatory bodies
Patent Status
Patent Pending
Clinical Trials
Phase III clinical trials demonstrated significant reduction in oxidative stress markers and improved patient outcomes in target populations. Ongoing post-marketing surveillance.
Lab Monitoring
- Liver function tests (LFTs) periodically
- Renal function tests if long-term use or impairment
Doctor Notes
- Emphasize adherence to prescribed dosage for optimal results.
- Counsel patients on potential drug interactions, especially with anticoagulants.
- Monitor liver function in patients with pre-existing hepatic conditions.
Patient Guidelines
- Take as directed by your doctor.
- Do not stop taking without consulting your doctor.
- Report any unusual side effects promptly.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness or fatigue in some individuals; exercise caution when driving or operating machinery.
Lifestyle Advice
- Maintain a balanced diet.
- Engage in regular physical activity.
- Avoid excessive alcohol consumption.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.