Prokult
Generic Name
Lactobacillus acidophilus + Bifidobacterium bifidum + Bifidobacterium lactis + Streptococcus thermophilus
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| prokult 4 billion powder | ৳ 47.00 | N/A |
Description
Overview of the medicine
Prokult-4-Billion-Powder is an oral probiotic supplement containing a blend of beneficial bacteria strains designed to restore and maintain a healthy gut flora. It helps in improving digestion, boosting immunity, and managing various gastrointestinal conditions.
Uses & Indications
Dosage
Adults
1 sachet once or twice daily, or as directed by physician.
Elderly
No specific dose adjustment needed.
Renal_impairment
No specific dose adjustment needed.
How to Take
Mix the powder in half a glass of water, milk, or juice. Do not mix with hot food or beverages as heat may destroy live bacteria. Take preferably with a meal.
Mechanism of Action
Probiotics work by colonizing the gut with beneficial bacteria, thereby competing with harmful pathogens for nutrients and attachment sites. They produce antimicrobial substances, modulate the immune system, improve gut barrier function, and assist in nutrient absorption and synthesis of vitamins.
Pharmacokinetics
Onset
Varies, often within days to weeks for noticeable effects.
Excretion
Excreted via feces.
Half life
Not applicable as they are live microorganisms colonizing the gut.
Absorption
Probiotics are generally not absorbed into the bloodstream. They exert their effects locally in the gastrointestinal tract. Their survival and colonization depend on gastric pH, bile acids, and competitive interactions with existing gut flora.
Metabolism
Metabolized by gut flora; contribute to metabolic activities within the gut.
Side Effects
Contraindications
- Known hypersensitivity to any component of the formulation
- Severely immunocompromised patients (e.g., those with central venous catheters, recent surgery, or critically ill patients) unless directed by a physician.
Drug Interactions
Antibiotics
May reduce the effectiveness of probiotics; separate administration by at least 2-3 hours.
Immunosuppressants
Use with caution in severely immunocompromised patients.
Storage
Store in a cool, dry place below 25°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overdose is unlikely to cause serious adverse effects due to the nature of probiotics. Symptomatic and supportive treatment is recommended if any discomfort occurs.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation. Consult a physician before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, Superstores, Online
Approval Status
Approved
Patent Status
Off-patent for generic components
Clinical Trials
Numerous clinical trials support the efficacy of probiotic combinations for various gastrointestinal conditions, particularly antibiotic-associated diarrhea and IBS. Specific trials for this exact formulation may vary.
Lab Monitoring
- Generally no specific lab monitoring required for routine use.
Doctor Notes
- Advise patients on proper administration (avoid hot liquids).
- Counsel on potential mild GI side effects.
- Emphasize not to exceed recommended dosage.
Patient Guidelines
- Take as directed, usually with a meal.
- Do not mix with hot liquids or food.
- Consult your doctor if symptoms persist or worsen.
- Store in a cool, dry place away from direct sunlight.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
No known effects on driving ability.
Lifestyle Advice
- Maintain a balanced diet rich in fiber (prebiotics) to support probiotic activity.
- Stay hydrated.
- Avoid excessive intake of processed foods and sugar.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.