Pulmoten
Generic Name
Pulmonexin Compound Tablet
Manufacturer
RespiroPharm Inc.
Country
USA
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| pulmoten 6250 mg tablet | ৳ 50.00 | ৳ 500.00 |
Description
Overview of the medicine
Pulmoten 6250 mg tablet is a novel multi-component medication designed for the comprehensive management of severe chronic respiratory conditions, particularly Idiopathic Pulmonary Fibrosis (IPF) and advanced Chronic Obstructive Pulmonary Disease (COPD). It combines mucolytic, anti-inflammatory, and antioxidant properties to improve lung function, reduce inflammation, and protect lung tissue from oxidative damage.
Uses & Indications
Dosage
Adults
One 6250 mg tablet once daily, preferably with food, or as directed by a physician.
Elderly
No specific dose adjustment is typically required for elderly patients, but careful monitoring is advised.
Renal_impairment
Use with caution; dose reduction may be necessary in severe renal impairment (CrCl <30 mL/min). Consult a physician.
How to Take
Pulmoten tablet should be swallowed whole with a glass of water. Do not crush, chew, or break the tablet. It can be taken with or without food, but taking it with food may reduce gastrointestinal upset.
Mechanism of Action
Pulmoten's multi-faceted action involves its mucolytic component breaking down thick mucus, easing expectoration. The anti-inflammatory agents reduce airway inflammation and fibrosis. The antioxidant components neutralize free radicals, protecting lung cells from oxidative stress and slowing disease progression.
Pharmacokinetics
Onset
Clinical effects observed within 1-2 days, with maximal benefits seen after 2-4 weeks of continuous therapy.
Excretion
Excreted mainly through urine and feces as metabolites and some unchanged drug.
Half life
Variable among components, generally ranging from 6 to 18 hours, supporting once or twice daily dosing.
Absorption
Rapidly absorbed from the GI tract, with peak plasma concentrations reached within 2-4 hours. Bioavailability is enhanced by a specialized formulation.
Metabolism
Primarily hepatic metabolism for some components, while others undergo renal or enzymatic degradation.
Side Effects
Contraindications
- Hypersensitivity to any component of the drug
- Acute asthma exacerbation
- Severe hepatic impairment
Drug Interactions
Warfarin
Increased risk of bleeding due to potential effect on coagulation. Monitor INR closely.
Other mucolytics
Concurrent use not recommended due to potential additive effects and increased side effects.
Immunosuppressants
May have altered efficacy or increased toxicity when co-administered.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms may include severe gastrointestinal upset, hepatic dysfunction, and exaggerated side effects. Treatment is symptomatic and supportive, including gastric lavage if recent ingestion, and liver support measures.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies the potential risk to the fetus. It is unknown if components are excreted in breast milk; caution advised in nursing mothers.
Side Effects
Contraindications
- Hypersensitivity to any component of the drug
- Acute asthma exacerbation
- Severe hepatic impairment
Drug Interactions
Warfarin
Increased risk of bleeding due to potential effect on coagulation. Monitor INR closely.
Other mucolytics
Concurrent use not recommended due to potential additive effects and increased side effects.
Immunosuppressants
May have altered efficacy or increased toxicity when co-administered.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms may include severe gastrointestinal upset, hepatic dysfunction, and exaggerated side effects. Treatment is symptomatic and supportive, including gastric lavage if recent ingestion, and liver support measures.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies the potential risk to the fetus. It is unknown if components are excreted in breast milk; caution advised in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Specialty pharmacies, hospital pharmacies
Approval Status
Approved by DGDA for emergency use
Patent Status
Patent pending
Clinical Trials
Currently undergoing Phase III clinical trials for broader indications and long-term efficacy in advanced IPF. Interim results show promising outcomes.
Lab Monitoring
- Liver function tests (ALT, AST, ALP, Bilirubin) - regularly, especially at baseline and during the first few months of therapy.
- Renal function tests (Creatinine, BUN) - especially in patients with pre-existing renal impairment.
- Complete Blood Count (CBC)
Doctor Notes
- Emphasize patient compliance for optimal therapeutic outcomes.
- Educate patients on symptoms of liver dysfunction and advise immediate reporting.
- Consider baseline and periodic LFTs and renal function tests.
Patient Guidelines
- Take the medication exactly as prescribed by your doctor.
- Do not stop taking the medicine without consulting your doctor, even if you feel better.
- Report any unusual symptoms, especially yellowing of skin/eyes, dark urine, or severe abdominal pain, to your doctor immediately.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
May cause dizziness or fatigue in some patients. If affected, avoid driving or operating heavy machinery.
Lifestyle Advice
- Avoid smoking as it can worsen respiratory conditions and reduce drug efficacy.
- Maintain a healthy diet and adequate hydration.
- Engage in regular, moderate exercise as tolerated to improve lung capacity.
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