Quintor
Generic Name
Ciprofloxacin
Manufacturer
Drug International Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| quintor 500 mg tablet | ৳ 10.00 | ৳ 80.00 |
| quintor 250 mg suspension | ৳ 60.00 | N/A |
Description
Overview of the medicine
Quintor contains Ciprofloxacin, a broad-spectrum fluoroquinolone antibiotic used to treat various bacterial infections.
Uses & Indications
Dosage
Adults
250-750 mg orally twice daily, depending on the infection severity and type.
Elderly
Dose adjustment may be necessary based on renal function.
Renal_impairment
Reduced dosage is required, e.g., 250-500 mg every 18-24 hours for severe impairment.
How to Take
May be taken with or without food. Avoid taking with dairy products or calcium-fortified juices alone. Take two hours before or six hours after iron, zinc, antacids, or sucralfate.
Mechanism of Action
Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, essential enzymes involved in DNA replication, transcription, repair, and recombination, leading to bacterial cell death.
Pharmacokinetics
Onset
Typically within 1-2 hours.
Excretion
Mainly renal excretion (approximately 50-70% as unchanged drug) and some biliary excretion.
Half life
About 3-5 hours.
Absorption
Rapidly and well absorbed from the gastrointestinal tract, bioavailability is about 70-80%.
Metabolism
Primarily hepatic metabolism to less active metabolites.
Side Effects
Contraindications
- Hypersensitivity to ciprofloxacin or other fluoroquinolones
- Concomitant use with Tizanidine
Drug Interactions
Caffeine
Reduced caffeine clearance.
Warfarin
Increased anticoagulant effect.
Tizanidine
Increased Tizanidine plasma concentrations, leading to hypotension and somnolence.
Theophylline
Increased theophylline plasma concentrations, leading to toxicity.
Antacids (containing Mg/Al), Iron, Zinc, Sucralfate
Decreased absorption of ciprofloxacin. Separate administration by several hours.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms include reversible renal toxicity. Management involves symptomatic and supportive care, including gastric lavage and adequate hydration. Hemodialysis or peritoneal dialysis may remove a small amount of ciprofloxacin.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies the potential risk to the fetus. Not recommended during lactation as it is excreted in breast milk and may cause adverse effects in the infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
Approved by FDA/DGDA
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have established ciprofloxacin's efficacy and safety for various bacterial infections since its introduction.
Lab Monitoring
- Renal function tests
- Liver function tests
- Complete blood count (CBC) if prolonged use
- Blood glucose monitoring in diabetic patients
Doctor Notes
- Counsel patients on potential tendon-related adverse effects and symptoms of peripheral neuropathy.
- Monitor renal function, especially in elderly and renally impaired patients.
- Avoid co-administration with tizanidine due to severe interaction risk.
Patient Guidelines
- Complete the full course of treatment even if symptoms improve.
- Stay well-hydrated.
- Avoid excessive sun exposure.
- Report any tendon pain, numbness, or tingling immediately.
Missed Dose Advice
Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double the dose.
Driving Precautions
May cause dizziness or lightheadedness, affecting the ability to drive or operate machinery. Exercise caution.
Lifestyle Advice
- Maintain good hygiene to prevent infections.
- Consume a balanced diet.
- Avoid alcohol during treatment as it may exacerbate side effects.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.