Radimet

Take Radimet 850 mg tablet orally with or after meals to reduce gastrointestinal side effects. Swallow the tablet whole with a glass of water, do not chew or crush it.

Metformin works primarily by decreasing hepatic glucose production (gluconeogenesis), decreasing intestinal absorption of glucose, and by improving insulin sensitivity (increasing peripheral glucose uptake and utilization). Unlike sulfonylureas, it does not stimulate insulin secretion and therefore does not cause hypoglycemia in monotherapy.

• Hypersensitivity to Metformin or any of its excipients.
• Severe renal impairment (eGFR < 30 mL/min/1.73 m²).
• Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma.
• Severe hepatic impairment, acute alcohol intoxication, dehydration, or conditions predisposing to lactic acidosis (e.g., heart failure requiring pharmacological treatment).

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.

Overdose of Metformin has been reported, including ingestion of amounts greater than 50 grams. Hypoglycemia has been reported in approximately 10% of cases, but lactic acidosis is the primary and most serious complication of Metformin overdose. Treatment of lactic acidosis requires supportive therapy, including hemodialysis.

Pregnancy Category B. Studies in animals have shown no risk to the fetus, but there are no adequate and well-controlled studies in pregnant women. Should be used during pregnancy only if clearly needed. Metformin is excreted into human milk, so a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

• Hypersensitivity to Metformin or any of its excipients.
• Severe renal impairment (eGFR < 30 mL/min/1.73 m²).
• Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma.
• Severe hepatic impairment, acute alcohol intoxication, dehydration, or conditions predisposing to lactic acidosis (e.g., heart failure requiring pharmacological treatment).

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.

Overdose of Metformin has been reported, including ingestion of amounts greater than 50 grams. Hypoglycemia has been reported in approximately 10% of cases, but lactic acidosis is the primary and most serious complication of Metformin overdose. Treatment of lactic acidosis requires supportive therapy, including hemodialysis.

Pregnancy Category B. Studies in animals have shown no risk to the fetus, but there are no adequate and well-controlled studies in pregnant women. Should be used during pregnancy only if clearly needed. Metformin is excreted into human milk, so a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.