Virecure
Generic Name
Ramdivir
Manufacturer
Global Pharma Inc.
Country
USA
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ramdivir 5 mg injection | ৳ 2,000.00 | N/A |
Description
Overview of the medicine
Ramdivir is a broad-spectrum antiviral agent indicated for the treatment of severe viral infections.
Uses & Indications
Dosage
Adults
Loading dose of 200 mg on Day 1, followed by 100 mg once daily for 5-10 days, administered intravenously.
Elderly
No specific dose adjustment required based on age, but monitor renal function.
Renal_impairment
Dose adjustment required; consider reducing to 50 mg daily or administering every other day based on creatinine clearance.
How to Take
Administer intravenously over 30-60 minutes. Do not administer as a rapid bolus injection.
Mechanism of Action
Ramdivir acts as a nucleoside analog that inhibits viral RNA-dependent RNA polymerase, thereby disrupting viral replication.
Pharmacokinetics
Onset
Within hours of administration.
Excretion
Mainly renal excretion of inactive metabolites.
Half life
Approximately 2-3 hours (parent compound); active metabolite has a longer half-life.
Absorption
Rapid and complete absorption following intravenous administration.
Metabolism
Primarily metabolized intracellularly to its active triphosphate form.
Side Effects
Contraindications
- Hypersensitivity to ramdivir or any components of the formulation.
- Severe hepatic impairment.
Drug Interactions
Chloroquine/Hydroxychloroquine
May reduce antiviral activity.
Nephrotoxic agents (e.g., aminoglycosides)
Increased risk of renal toxicity.
Storage
Store below 30°C. Do not freeze. Protect from light. Keep out of reach of children.
Overdose
No specific antidote. Management involves symptomatic and supportive care, including monitoring renal and hepatic function.
Pregnancy & Lactation
Category C. Use only if potential benefit outweighs potential risk to the fetus. Not recommended during breastfeeding due to unknown excretion into milk.
Side Effects
Contraindications
- Hypersensitivity to ramdivir or any components of the formulation.
- Severe hepatic impairment.
Drug Interactions
Chloroquine/Hydroxychloroquine
May reduce antiviral activity.
Nephrotoxic agents (e.g., aminoglycosides)
Increased risk of renal toxicity.
Storage
Store below 30°C. Do not freeze. Protect from light. Keep out of reach of children.
Overdose
No specific antidote. Management involves symptomatic and supportive care, including monitoring renal and hepatic function.
Pregnancy & Lactation
Category C. Use only if potential benefit outweighs potential risk to the fetus. Not recommended during breastfeeding due to unknown excretion into milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Hospitals and specialized clinics
Approval Status
Approved by regulatory authorities (e.g., FDA, DGDA)
Patent Status
Patented
WHO Essential Medicine
YesClinical Trials
Extensive Phase III clinical trials demonstrated efficacy and safety in hospitalized patients with severe viral infections, leading to regulatory approval.
Lab Monitoring
- Baseline and periodic renal function tests (serum creatinine, BUN)
- Liver function tests (ALT, AST, bilirubin)
- Complete blood count (CBC)
Doctor Notes
- Monitor patients for signs of hypersensitivity reactions, especially during initial doses.
- Adjust dosage based on renal function, and discontinue if severe adverse renal or hepatic events occur.
Patient Guidelines
- Report any severe side effects immediately to your healthcare provider.
- Ensure you complete the full course of treatment as prescribed.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If a dose is missed, administer it as soon as possible. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness; avoid driving or operating heavy machinery if you experience this side effect.
Lifestyle Advice
- Maintain adequate hydration during treatment.
- Get plenty of rest to support recovery.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.