Reflexen
Generic Name
Eperisone Hydrochloride
Manufacturer
XYZ Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| reflexen 10 mg tablet | ৳ 8.00 | ৳ 80.00 |
Description
Overview of the medicine
Eperisone is a centrally acting muscle relaxant used for the symptomatic treatment of muscle spasm and spasticity, often associated with various musculoskeletal conditions.
Uses & Indications
Dosage
Adults
Usually 10 mg three times daily after meals, or as directed by physician. Dosage may be adjusted based on symptoms.
Elderly
No specific dose adjustment is usually required, but caution should be exercised. Start with a lower dose.
Renal_impairment
Use with caution. Dose adjustment may be necessary in severe renal impairment.
How to Take
Swallow the tablet whole with water after meals. Do not chew or crush.
Mechanism of Action
Eperisone acts by relaxing skeletal muscles through action on the central nervous system, mainly by inhibiting the activity of gamma-motor neurons and acting on the spinal cord. It also exhibits vasodilator effects.
Pharmacokinetics
Onset
Within a few hours of administration.
Excretion
Primarily excreted in the urine, with a small amount in feces.
Half life
Approximately 1-3 hours.
Absorption
Well absorbed orally after administration. Peak plasma concentration reached within 1-2 hours.
Metabolism
Extensively metabolized in the liver (mainly via CYP450 enzymes).
Side Effects
Contraindications
- Hypersensitivity to Eperisone Hydrochloride or any component of the tablet
- Severe liver impairment
Drug Interactions
Tolperisone
Concurrent use with tolperisone may increase the risk of side effects.
Other CNS Depressants
Concurrent use with other CNS depressants or alcohol may enhance drowsiness and sedation.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment should be initiated. Contact a poison control center or emergency services immediately.
Pregnancy & Lactation
Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Use only if clearly needed and the benefits outweigh the risks.
Side Effects
Contraindications
- Hypersensitivity to Eperisone Hydrochloride or any component of the tablet
- Severe liver impairment
Drug Interactions
Tolperisone
Concurrent use with tolperisone may increase the risk of side effects.
Other CNS Depressants
Concurrent use with other CNS depressants or alcohol may enhance drowsiness and sedation.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment should be initiated. Contact a poison control center or emergency services immediately.
Pregnancy & Lactation
Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Use only if clearly needed and the benefits outweigh the risks.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from the date of manufacture, check the packaging for specific expiry date.
Availability
Pharmacies, Hospitals
Approval Status
Approved (DGDA)
Patent Status
Off-patent
Clinical Trials
Clinical trials have demonstrated Eperisone's efficacy and safety in relieving muscle spasticity and associated symptoms.
Lab Monitoring
- Liver function tests (especially with prolonged use or in patients with pre-existing liver conditions).
Doctor Notes
- Advise patients about potential drowsiness and to avoid activities requiring mental alertness, such as driving or operating machinery.
- Counsel patients on the importance of taking the medicine after meals to reduce GI upset.
Patient Guidelines
- Take the medicine exactly as prescribed by your doctor.
- Do not exceed the recommended dose.
- Report any unusual side effects to your doctor.
- Avoid alcohol while taking this medicine.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Eperisone may cause drowsiness, dizziness, or blurred vision. Avoid driving or operating machinery if you experience these effects.
Lifestyle Advice
- Avoid activities requiring mental alertness, such as driving or operating heavy machinery, especially when starting treatment.
- Maintain a healthy lifestyle, including regular exercise and a balanced diet.
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