Deep intramuscular injection into the gluteal muscle. Ensure correct injection technique to avoid nerve damage. Do not administer intravenously.

Diclofenac inhibits cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Thiamine, Pyridoxine, and Cyanocobalamin act as coenzymes in various metabolic processes, particularly important for nerve function and myelin sheath formation, and contribute to nerve regeneration and pain modulation.

• •Hypersensitivity to Diclofenac, aspirin, or other NSAIDs, or any B vitamins
• •Active gastrointestinal bleeding or ulceration
• •Severe renal or hepatic impairment
• •Severe heart failure
• •History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
• •Last trimester of pregnancy

Store below 30°C, protected from light and moisture. Do not freeze.

Symptoms: Lethargy, drowsiness, nausea, vomiting, epigastric pain, GI bleeding, rare acute renal failure, hepatic damage. Management: Symptomatic and supportive treatment. No specific antidote. Gastric lavage and activated charcoal may be considered if recent oral ingestion.

Pregnancy: Contraindicated in the last trimester due to potential premature closure of the fetal ductus arteriosus. Use in first two trimesters only if clearly necessary and potential benefits outweigh risks. Lactation: Diclofenac and its metabolites pass into breast milk in small amounts; use with caution. B vitamins are generally safe.