Take orally with or without food. To maximize absorption and minimize gastrointestinal upset, some prefer to take it with food. Complete the full prescribed course of treatment.

Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to bacterial cell lysis and death.

• •Hypersensitivity to penicillin antibiotics or any component of the formulation.
• •History of a severe hypersensitivity reaction (e.g., anaphylaxis) to any other beta-lactam agent (e.g., cephalosporins, carbapenems).
• •Infectious mononucleosis (due to increased risk of rash).

Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.

Symptoms of overdose may include gastrointestinal symptoms (nausea, vomiting, diarrhea), electrolyte imbalance, and crystalluria (renal failure may occur in severe cases). In patients with impaired renal function or those receiving very high doses, neurological effects including convulsions may occur. Treatment is largely symptomatic and supportive. Hemodialysis can remove amoxicillin from circulation.

Pregnancy Category B. Studies in animals have shown no evidence of harm to the fetus, but adequate and well-controlled studies in pregnant women are lacking. Generally considered safe for use during pregnancy when clearly needed. Excreted in breast milk in small amounts; generally considered compatible with breastfeeding, but monitor the infant for diarrhea, candidiasis, or allergic sensitization.