Renaliv
Generic Name
Cranberry Extract, D-Mannose, Potassium Magnesium Citrate
Manufacturer
Various (e.g., General Pharmaceuticals Ltd., Square Pharmaceuticals Ltd.)
Country
Bangladesh, India, etc.
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| renaliv 5 mg tablet | ৳ 15.00 | ৳ 150.00 |
Description
Overview of the medicine
Renaliv is a dietary supplement formulated to support kidney health and urinary tract function. It typically contains ingredients like cranberry extract, D-mannose, and potassium magnesium citrate, known for their roles in preventing urinary tract infections and kidney stone formation.
Uses & Indications
Dosage
Adults
Typically 1-2 tablets/capsules once or twice daily, or as directed by a physician. For powder, usually 1 sachet daily dissolved in water.
Elderly
Same as adult dosage, unless specific renal impairment considerations exist.
Renal_impairment
Generally considered safe, but consultation with a physician is advised, especially for severe renal impairment due to potassium/magnesium content.
How to Take
To be taken orally, with or without food. For powders, dissolve in a glass of water and drink immediately.
Mechanism of Action
Cranberry extract helps prevent bacteria (especially E. coli) from adhering to the urinary tract walls. D-mannose also binds to bacteria, facilitating their excretion. Potassium and magnesium citrates help to alkalinize urine, reducing the supersaturation of calcium oxalate and uric acid, thereby preventing kidney stone formation.
Pharmacokinetics
Onset
Effects on urinary pH and bacterial adhesion can be observed within hours to days.
Excretion
Primarily renal (D-mannose, citrates, unabsorbed cranberry components).
Half life
Variable for individual components.
Absorption
Cranberry proanthocyanidins have limited systemic absorption; D-mannose is absorbed, but a significant portion is excreted unchanged in urine. Citrates are absorbed and metabolized.
Metabolism
D-mannose is minimally metabolized; citrates are metabolized in the liver to bicarbonate.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation
- Severe renal impairment (especially for potassium/magnesium citrate components)
- Hyperkalemia
Drug Interactions
Diuretics
Potassium-sparing diuretics taken with potassium magnesium citrate may increase the risk of hyperkalemia.
Warfarin/Anticoagulants
Cranberry may enhance the effect of anticoagulants, increasing the risk of bleeding.
Antacids containing aluminum
May reduce the absorption of citrate.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Overdose may lead to gastrointestinal upset, diarrhea, or electrolyte imbalance (e.g., hyperkalemia). Symptomatic and supportive treatment is recommended.
Pregnancy & Lactation
Consult a physician before use during pregnancy or lactation. While generally considered safe, specific studies may be limited.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation
- Severe renal impairment (especially for potassium/magnesium citrate components)
- Hyperkalemia
Drug Interactions
Diuretics
Potassium-sparing diuretics taken with potassium magnesium citrate may increase the risk of hyperkalemia.
Warfarin/Anticoagulants
Cranberry may enhance the effect of anticoagulants, increasing the risk of bleeding.
Antacids containing aluminum
May reduce the absorption of citrate.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Overdose may lead to gastrointestinal upset, diarrhea, or electrolyte imbalance (e.g., hyperkalemia). Symptomatic and supportive treatment is recommended.
Pregnancy & Lactation
Consult a physician before use during pregnancy or lactation. While generally considered safe, specific studies may be limited.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from manufacturing date
Availability
Pharmacies, online stores, health stores
Approval Status
Approved as a dietary supplement/nutraceutical
Patent Status
Proprietary formulation, specific ingredients may be patented
Clinical Trials
Clinical studies support the efficacy of cranberry and D-mannose in UTI prevention, and citrates in kidney stone prevention. Specific trials for 'Renaliv' brand may vary.
Lab Monitoring
- For patients with renal impairment or those at risk of electrolyte imbalance, periodic monitoring of serum electrolytes (potassium, magnesium) and renal function may be advised.
- Urinalysis for UTI or stone components.
Doctor Notes
- Advise patients on adequate fluid intake.
- Counsel on dietary modifications for kidney stone prevention if applicable.
- Monitor for signs of UTI or stone recurrence.
Patient Guidelines
- Take as directed by your physician or pharmacist.
- Ensure adequate fluid intake throughout the day.
- Inform your doctor about all other medications and supplements you are taking.
- Do not exceed the recommended dose.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double dose.
Driving Precautions
Renaliv is not known to impair the ability to drive or operate machinery.
Lifestyle Advice
- Maintain good hydration by drinking plenty of water.
- Adopt a balanced diet rich in fruits and vegetables.
- Avoid excessive intake of highly processed foods and sugary drinks.
- For kidney stone prevention, dietary modifications (e.g., low sodium, appropriate calcium intake) may be beneficial.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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