Residon
Generic Name
Risperidone
Manufacturer
MediCo Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| residon 1 mg tablet | ৳ 3.00 | ৳ 30.00 |
Description
Overview of the medicine
Risperidone is an atypical antipsychotic used to treat schizophrenia, bipolar mania, and irritability associated with autistic disorder.
Uses & Indications
Dosage
Adults
Schizophrenia: initially 2 mg/day, target 4-6 mg/day. Bipolar mania: initially 2-3 mg/day, range 1-6 mg/day. Autistic irritability: 0.5-1 mg/day. (Specifics depend on condition and patient)
Elderly
Lower initial doses, slower titration.
Renal_impairment
Lower initial doses (e.g., 0.5 mg BID), slower titration.
How to Take
Oral, with or without food.
Mechanism of Action
Selective monoaminergic antagonist with high affinity for serotonin 5-HT2 and dopamine D2 receptors.
Pharmacokinetics
Onset
Effects can be seen within days to weeks.
Excretion
Primarily renal (70%), some fecal (14%).
Half life
Parent drug 3 hours, active metabolite 9-hydroxyrisperidone 20 hours.
Absorption
Rapidly absorbed, peak plasma concentration within 1 hour.
Metabolism
Extensively metabolized in the liver by CYP2D6 to 9-hydroxyrisperidone (active metabolite).
Side Effects
Contraindications
- Hypersensitivity to risperidone or any component.
- Concomitant use with drugs that prolong QT interval (relative).
Drug Interactions
Antihypertensives
Increased hypotensive effect.
Dopamine agonists (e.g., levodopa)
Antagonistic effects.
CNS depressants (alcohol, benzodiazepines)
Additive CNS depression.
CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
Increase risperidone plasma levels.
Storage
Store below 30°C, protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms include drowsiness, tachycardia, hypotension, extrapyramidal symptoms. Management: supportive care, gastric lavage, activated charcoal.
Pregnancy & Lactation
Pregnancy: Use only if potential benefit outweighs risk (Category C). Lactation: Excreted in breast milk, avoid or use with caution.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years.
Availability
Pharmacies, hospitals
Approval Status
Approved by regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Numerous trials for schizophrenia, bipolar disorder, and autism.
Lab Monitoring
- Blood pressure (especially orthostatic)
- Blood glucose/lipid profile (due to metabolic risks)
- Prolactin levels
- ECG (if cardiac risk factors)
Doctor Notes
- Monitor for metabolic changes (weight, glucose, lipids).
- Assess for extrapyramidal symptoms and tardive dyskinesia regularly.
- Caution in elderly patients with dementia-related psychosis.
Patient Guidelines
- Take as prescribed, do not stop abruptly.
- Avoid alcohol.
- Report unusual muscle movements.
- Be aware of dizziness or lightheadedness, especially when standing up.
Missed Dose Advice
Take as soon as remembered unless it's almost time for the next dose. Do not double dose.
Driving Precautions
May cause drowsiness or dizziness; avoid driving or operating heavy machinery until effects are known.
Lifestyle Advice
- Maintain a healthy diet and exercise to mitigate weight gain. Avoid overheating and dehydration.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.