Restovit
Generic Name
Cyproheptadine Hydrochloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| restovit 5 mg syrup | ৳ 35.00 | N/A |
Description
Overview of the medicine
Restovit-5mg syrup contains Cyproheptadine which is an antihistamine with additional appetite stimulating properties. It is used to treat allergic conditions and to stimulate appetite.
Uses & Indications
Dosage
Adults
Typically 4 mg (1 measuring spoonful or 5 ml) three times daily. Max dose 0.5 mg/kg/day.
Elderly
Lower initial doses are recommended, adjusted according to response and tolerability.
Renal_impairment
Use with caution; dosage adjustment may be necessary due to renal excretion of metabolites.
How to Take
Take orally, with or without food. Can be taken at bedtime due to sedative effects.
Mechanism of Action
Cyproheptadine acts as a potent H1-receptor antagonist, blocking the effects of histamine. It also has antiserotonergic activity, which is believed to contribute to its appetite-stimulating effects.
Pharmacokinetics
Onset
Within 15-30 minutes.
Excretion
Excreted primarily via urine as metabolites, with a small portion excreted in feces.
Half life
Approximately 16 hours.
Absorption
Readily absorbed from the gastrointestinal tract.
Metabolism
Extensively metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to cyproheptadine or any component of the formulation
- Newborn or premature infants
- Nursing mothers
- Narrow-angle glaucoma
- Urinary retention
- Elderly, debilitated patients
Drug Interactions
MAO inhibitors
Prolongation and intensification of anticholinergic effects.
Anticholinergics
Increased anticholinergic side effects.
CNS depressants (alcohol, sedatives, hypnotics)
Increased sedation.
Storage
Store in a cool, dry place, below 30°C. Protect from light. Keep out of reach of children.
Overdose
Symptoms of overdose include severe drowsiness, dizziness, dilated pupils, dry mouth, flushed skin, fever, agitation, confusion, hallucinations. In severe cases, coma, seizures, and respiratory depression may occur. Management involves symptomatic and supportive care. Gastric lavage may be considered if recent ingestion.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Contraindicated in nursing mothers as it may be excreted in breast milk and cause drowsiness in the infant.
Side Effects
Contraindications
- Hypersensitivity to cyproheptadine or any component of the formulation
- Newborn or premature infants
- Nursing mothers
- Narrow-angle glaucoma
- Urinary retention
- Elderly, debilitated patients
Drug Interactions
MAO inhibitors
Prolongation and intensification of anticholinergic effects.
Anticholinergics
Increased anticholinergic side effects.
CNS depressants (alcohol, sedatives, hypnotics)
Increased sedation.
Storage
Store in a cool, dry place, below 30°C. Protect from light. Keep out of reach of children.
Overdose
Symptoms of overdose include severe drowsiness, dizziness, dilated pupils, dry mouth, flushed skin, fever, agitation, confusion, hallucinations. In severe cases, coma, seizures, and respiratory depression may occur. Management involves symptomatic and supportive care. Gastric lavage may be considered if recent ingestion.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Contraindicated in nursing mothers as it may be excreted in breast milk and cause drowsiness in the infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date.
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Generic available
Clinical Trials
Cyproheptadine has been extensively studied for its antihistaminic and appetite stimulant properties, with numerous clinical trials supporting its efficacy in these areas.
Lab Monitoring
- No routine lab monitoring is generally required. Monitor for blood dyscrasias in long-term therapy.
Doctor Notes
- Advise patients about potential sedation, especially when starting therapy.
- Consider alternative therapies if excessive weight gain is a concern.
Patient Guidelines
- Avoid driving or operating heavy machinery until you know how the medicine affects you.
- Avoid alcohol while taking this medicine.
- Do not exceed the recommended dose.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause drowsiness and dizziness. Patients should be warned not to operate vehicles or hazardous machinery until it is determined that they do not become drowsy or dizzy from cyproheptadine.
Lifestyle Advice
- Maintain a balanced diet.
- Engage in regular physical activity if appetite stimulation leads to weight gain concern.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.