Rosunor 10 mg Tablet should be taken orally, once daily, with or without food. It can be taken at any time of the day, but consistency is recommended (e.g., always at bedtime). Swallow the tablet whole with water.

Rosuvastatin is an HMG-CoA reductase inhibitor. It selectively and competitively inhibits the enzyme HMG-CoA reductase, which is responsible for cholesterol synthesis in the liver. This leads to a decrease in hepatic cholesterol, which upregulates the number of LDL receptors on the hepatocyte surface, enhancing uptake and catabolism of LDL. It also inhibits hepatic synthesis of VLDL, thereby reducing the total number of VLDL and LDL particles.

• •Hypersensitivity to Rosuvastatin or any component of the formulation
• •Active liver disease, including unexplained persistent elevations of serum transaminases
• •Severe renal impairment (CrCl <30 mL/min)
• •Pregnancy and lactation
• •Concomitant use with cyclosporine

Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.

There is no specific treatment for Rosuvastatin overdose. In case of overdose, initiate symptomatic and supportive measures. Liver function tests and CK levels should be monitored. Hemodialysis is unlikely to be of benefit.

Rosunor 10 mg Tablet is contraindicated during pregnancy and lactation. Women of childbearing potential should use adequate contraceptive measures during treatment. If pregnancy occurs, stop the medication immediately.