Rotomycin
Generic Name
Rotomycin 300 mg Tablet
Manufacturer
MediHealth Pharmaceuticals
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| rotomycin 300 mg tablet | ৳ 14.00 | N/A |
Description
Overview of the medicine
Rotomycin 300 mg Tablet is a macrolide antibiotic used to treat a variety of bacterial infections, including respiratory tract infections, skin infections, and certain sexually transmitted infections.
Uses & Indications
Dosage
Adults
300 mg once daily for 5-7 days, or as directed by physician.
Elderly
No specific dose adjustment required, but caution advised.
Renal_impairment
No dose adjustment needed for mild to moderate impairment; caution in severe impairment.
How to Take
Should be taken orally with or without food. Swallow whole, do not crush or chew.
Mechanism of Action
Rotomycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the translocation of peptidyl tRNA.
Pharmacokinetics
Onset
1-2 hours
Excretion
Primarily excreted in bile and feces; minor renal excretion.
Half life
Approximately 8-12 hours
Absorption
Rapidly absorbed after oral administration; bioavailability approximately 60%.
Metabolism
Extensively metabolized in the liver, primarily via CYP3A4.
Side Effects
Contraindications
- Hypersensitivity to rotomycin or other macrolides
- Severe hepatic impairment
- Concurrent use with certain QT-prolonging drugs
Drug Interactions
Warfarin
Increased anticoagulant effect. Monitor INR closely.
Statins (e.g., Simvastatin)
Increased risk of myopathy/rhabdomyolysis due to CYP3A4 inhibition.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, abdominal pain, and diarrhea. Treatment is symptomatic and supportive. Gastric lavage may be considered.
Pregnancy & Lactation
Use only if clearly needed. Consult your doctor.
Side Effects
Contraindications
- Hypersensitivity to rotomycin or other macrolides
- Severe hepatic impairment
- Concurrent use with certain QT-prolonging drugs
Drug Interactions
Warfarin
Increased anticoagulant effect. Monitor INR closely.
Statins (e.g., Simvastatin)
Increased risk of myopathy/rhabdomyolysis due to CYP3A4 inhibition.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, abdominal pain, and diarrhea. Treatment is symptomatic and supportive. Gastric lavage may be considered.
Pregnancy & Lactation
Use only if clearly needed. Consult your doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies nationwide
Approval Status
Approved by regulatory authorities
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have demonstrated efficacy and safety in various bacterial infections.
Lab Monitoring
- Liver function tests (LFTs) if prolonged use
- Renal function tests if co-morbidities exist
Doctor Notes
- Monitor for signs of C. difficile infection.
- Advise patients on completing the full course.
Patient Guidelines
- Complete the full course of antibiotics even if symptoms improve.
- Do not share this medicine with others.
- Inform your doctor about all other medicines you are taking.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness in some patients; avoid driving or operating machinery until you know how Rotomycin affects you.
Lifestyle Advice
- Maintain good hygiene to prevent reinfection.
- Drink plenty of fluids.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.