Roxiquin
Generic Name
Roxiquin 200 mg Tablet
Manufacturer
Global Pharma Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| roxiquin 200 mg tablet | ৳ 12.00 | ৳ 120.00 |
Description
Overview of the medicine
Roxiquin 200 mg Tablet is a broad-spectrum fluoroquinolone antibiotic used to treat various bacterial infections.
Uses & Indications
Dosage
Adults
Typically 200 mg orally twice daily, or as directed by a physician. Dosage and duration depend on the type and severity of infection.
Elderly
Similar to adult dosage, but dose adjustment may be necessary based on renal function.
Renal_impairment
Dose adjustment required for patients with creatinine clearance <30 mL/min. Consult a physician for specific recommendations.
How to Take
Roxiquin tablets should be swallowed whole with a glass of water, with or without food. Avoid taking with dairy products, antacids, or iron/zinc supplements within 2 hours.
Mechanism of Action
It works by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication, transcription, repair, and recombination, leading to bacterial cell death.
Pharmacokinetics
Onset
Onset of action typically occurs within 1-2 hours after administration.
Excretion
Primarily excreted renally (via urine), both as unchanged drug and metabolites.
Half life
The elimination half-life is approximately 3-5 hours.
Absorption
Rapidly and well absorbed from the gastrointestinal tract after oral administration, with good bioavailability.
Metabolism
Undergoes minor hepatic metabolism to several less active metabolites.
Side Effects
Contraindications
- Hypersensitivity to Roxiquin or other fluoroquinolones.
- History of tendon disorders (e.g., tendinitis, tendon rupture) associated with quinolone use.
- Concomitant use with Tizanidine.
Drug Interactions
NSAIDs
May increase the risk of CNS stimulation and convulsive seizures.
Warfarin
May increase anticoagulant effects of warfarin, requiring INR monitoring.
Tizanidine
Concomitant use is contraindicated due to increased risk of hypotension and sedation.
Antacids, Iron, Zinc, Sucralfate
May decrease Roxiquin absorption. Take Roxiquin at least 2 hours before or 6 hours after these agents.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, gastric lavage may be performed. Symptomatic and supportive treatment should be initiated. Adequate hydration should be maintained.
Pregnancy & Lactation
Generally not recommended during pregnancy and lactation due to potential risks to the fetus/infant (e.g., cartilage damage). Use only if the potential benefit justifies the potential risk, under strict medical supervision.
Side Effects
Contraindications
- Hypersensitivity to Roxiquin or other fluoroquinolones.
- History of tendon disorders (e.g., tendinitis, tendon rupture) associated with quinolone use.
- Concomitant use with Tizanidine.
Drug Interactions
NSAIDs
May increase the risk of CNS stimulation and convulsive seizures.
Warfarin
May increase anticoagulant effects of warfarin, requiring INR monitoring.
Tizanidine
Concomitant use is contraindicated due to increased risk of hypotension and sedation.
Antacids, Iron, Zinc, Sucralfate
May decrease Roxiquin absorption. Take Roxiquin at least 2 hours before or 6 hours after these agents.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, gastric lavage may be performed. Symptomatic and supportive treatment should be initiated. Adequate hydration should be maintained.
Pregnancy & Lactation
Generally not recommended during pregnancy and lactation due to potential risks to the fetus/infant (e.g., cartilage damage). Use only if the potential benefit justifies the potential risk, under strict medical supervision.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from the date of manufacture.
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA/FDA
Patent Status
Expired
WHO Essential Medicine
YesClinical Trials
Clinical trials have evaluated the efficacy and safety of Roxiquin in the treatment of various bacterial infections, demonstrating favorable outcomes in studies supporting its indications.
Lab Monitoring
- Renal function tests (creatinine, BUN)
- Liver function tests (ALT, AST)
- Complete Blood Count (CBC) if prolonged therapy
- INR for patients on warfarin
Doctor Notes
- Emphasize the importance of completing the full course of therapy to prevent resistance.
- Counsel patients on the risk of tendinitis and tendon rupture, advising them to report symptoms immediately.
- Review potential drug interactions, especially with antacids, warfarin, and tizanidine.
Patient Guidelines
- Complete the entire course of medication even if symptoms improve.
- Stay well-hydrated by drinking plenty of fluids.
- Avoid excessive exposure to sunlight or artificial UV light, as it can cause photosensitivity.
- Report any tendon pain, swelling, or inflammation immediately to your doctor.
- Avoid taking with dairy products, antacids, or iron/zinc supplements.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Roxiquin may cause dizziness or lightheadedness, which could impair your ability to drive or operate machinery. If you experience these effects, avoid such activities.
Lifestyle Advice
- Avoid strenuous physical activity during treatment to minimize the risk of tendon injury.
- Maintain good hygiene to prevent reinfection.
- Adopt a balanced diet.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.