SabuRelief
Generic Name
Sabutanol
Manufacturer
Generic Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sabutanol 2 mg tablet | ৳ 0.26 | N/A |
Description
Overview of the medicine
Sabutanol 2 mg tablet is a bronchodilator used to relieve symptoms of asthma and chronic obstructive pulmonary disease (COPD), such as coughing, wheezing, and shortness of breath. It works by relaxing the muscles in the airways, making breathing easier.
Uses & Indications
Dosage
Adults
Usually 2-4 mg three or four times daily. A single dose of 8 mg may be used in some patients.
Elderly
A starting dose of 2 mg three or four times daily, adjusting according to response.
Renal_impairment
No specific dose adjustment is usually required, but caution is advised in severe renal impairment.
How to Take
Take orally with or without food. Follow your doctor's instructions regarding frequency and duration.
Mechanism of Action
Sabutanol selectively stimulates beta-2 adrenergic receptors in the smooth muscle of the bronchial tree, leading to relaxation of the bronchial smooth muscles and bronchodilation. This action helps to alleviate bronchospasm.
Pharmacokinetics
Onset
Bronchodilation typically occurs within 30 minutes to 1 hour after oral administration.
Excretion
Primarily excreted in the urine as metabolites and unchanged drug.
Half life
Approximately 4-6 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract.
Metabolism
Undergoes extensive first-pass metabolism in the liver to an inactive sulfate conjugate.
Side Effects
Contraindications
- Hypersensitivity to sabutanol or any component of the formulation.
- Threatened abortion (oral salbutamol preparations).
Drug Interactions
Beta-blockers
May inhibit the effect of sabutanol and cause severe bronchospasm in asthmatic patients.
MAOIs and TCAs
May potentiate the cardiovascular effects of sabutanol.
Diuretics (e.g., loop or thiazide diuretics)
May potentiate the risk of hypokalemia.
Storage
Store below 30°C in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include tachycardia, tremors, palpitations, headache, hypokalemia, and hyperglycemia. Management is supportive and symptomatic, with cardiac monitoring and correction of electrolyte imbalances.
Pregnancy & Lactation
Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. Sabutanol is excreted in breast milk; caution should be exercised when administered to a nursing woman.
Side Effects
Contraindications
- Hypersensitivity to sabutanol or any component of the formulation.
- Threatened abortion (oral salbutamol preparations).
Drug Interactions
Beta-blockers
May inhibit the effect of sabutanol and cause severe bronchospasm in asthmatic patients.
MAOIs and TCAs
May potentiate the cardiovascular effects of sabutanol.
Diuretics (e.g., loop or thiazide diuretics)
May potentiate the risk of hypokalemia.
Storage
Store below 30°C in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include tachycardia, tremors, palpitations, headache, hypokalemia, and hyperglycemia. Management is supportive and symptomatic, with cardiac monitoring and correction of electrolyte imbalances.
Pregnancy & Lactation
Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. Sabutanol is excreted in breast milk; caution should be exercised when administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from the date of manufacture.
Availability
Globally available in pharmacies and hospitals
Approval Status
Approved by major regulatory bodies (e.g., FDA, EMA, DGDA)
Patent Status
Expired
WHO Essential Medicine
YesClinical Trials
Extensively studied in numerous clinical trials demonstrating its efficacy and safety in the management of asthma and COPD across various age groups.
Lab Monitoring
- Serum potassium levels (especially in severe acute asthma, concomitant use of xanthines, steroids, or diuretics, and hypoxemia).
- Blood glucose levels (rarely, especially in diabetic patients).
Doctor Notes
- Educate patients on the difference between 'reliever' and 'preventer' medications.
- Advise patients to seek medical advice if they need to use the reliever more frequently than usual.
- Monitor for signs of cardiovascular effects and hypokalemia, especially in high-risk patients.
Patient Guidelines
- Do not exceed the prescribed dose or frequency.
- Seek immediate medical attention if symptoms worsen or if the usual dose becomes less effective.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double the dose to make up for a missed one.
Driving Precautions
Sabutanol may cause tremor or dizziness in some patients, which could affect the ability to drive or operate machinery. Exercise caution until you know how the medicine affects you.
Lifestyle Advice
- Avoid known asthma triggers (e.g., smoke, allergens).
- Maintain a healthy lifestyle, including regular exercise and a balanced diet.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.