RespiraSalt
Generic Name
Saltide
Manufacturer
GlobalPharma Inc.
Country
USA
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| saltide 25 mg respirator solution | ৳ 16.00 | N/A |
Description
Overview of the medicine
Saltide is a synthetic corticosteroid delivered as a respirator solution for the management of chronic inflammatory airway diseases such as asthma and COPD.
Uses & Indications
Dosage
Adults
25 mg (1 ampoule) via nebulizer once daily, or 12.5 mg twice daily, adjusted based on clinical response.
Elderly
Same as adults, with caution and monitoring for systemic side effects.
Renal_impairment
No specific dosage adjustment required, but use with caution in severe renal impairment.
How to Take
For nebulization only. Administer using a jet nebulizer with a mouthpiece or face mask. Do not swallow. Do not inject. Rinse mouth thoroughly with water after each use.
Mechanism of Action
Saltide acts as a potent anti-inflammatory agent by binding to glucocorticoid receptors in airway cells, inhibiting the release of inflammatory mediators and reducing airway hyper-responsiveness.
Pharmacokinetics
Onset
Within hours, full therapeutic effect within days to weeks of regular use.
Excretion
Primarily via bile and feces; a small amount via urine.
Half life
Approximately 3-5 hours (systemic), longer in the lungs.
Absorption
Rapidly absorbed from the lungs; low systemic bioavailability due to extensive first-pass metabolism.
Metabolism
Extensively metabolized in the liver via CYP450 enzymes, primarily CYP3A4.
Side Effects
Contraindications
- •Hypersensitivity to Saltide or any excipients
- •Primary treatment of status asthmaticus or other acute episodes of asthma or COPD where intensive measures are required
Drug Interactions
Beta-blockers
Could reduce the bronchodilatory effect of concomitant bronchodilators and should be used with caution.
CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
May significantly increase systemic exposure to Saltide, leading to potential adrenal suppression. Co-administration should be avoided or carefully monitored.
Storage
Store at 20-25°C (68-77°F); excursions permitted to 15-30°C (59-86°F). Protect from light and freezing. Keep out of reach of children.
Overdose
Acute overdose is unlikely to cause severe systemic effects. Chronic overdose may lead to adrenal suppression and Cushingoid features. Management includes symptomatic and supportive care; dose reduction or temporary discontinuation may be required.
Pregnancy & Lactation
Use only if the potential benefit justifies the potential risk to the fetus/infant. Consult a physician to discuss risks and benefits.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies, hospitals
Approval Status
Approved by regulatory authorities (e.g., FDA/DGDA)
Patent Status
Under patent
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Global Brand Names
International brand names for this medicine
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