Samprid
Generic Name
Samprid 80 mg Tablet (Hypothetical Active Ingredient)
Manufacturer
MediCore Pharmaceuticals Ltd. (Hypothetical)
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| samprid 80 mg tablet | ৳ 8.00 | ৳ 80.00 |
Description
Overview of the medicine
Samprid 80 mg Tablet is a hypothetical medication indicated for the management of essential hypertension. It acts by relaxing and widening blood vessels to lower blood pressure.
Uses & Indications
Dosage
Adults
Initially 40 mg once daily, adjusted to 80 mg once daily based on blood pressure response. Maximum 160 mg/day.
Elderly
No specific dose adjustment required, but initiate at lower dose (e.g., 40 mg) with careful monitoring.
Renal_impairment
For creatinine clearance <30 mL/min, initial dose 40 mg once daily; monitor renal function closely.
How to Take
Take orally with a glass of water, with or without food. It is recommended to take the tablet at the same time each day.
Mechanism of Action
The hypothetical active ingredient in Samprid 80 mg Tablet acts as a peripheral vasodilator, directly relaxing vascular smooth muscle, leading to a reduction in systemic vascular resistance and subsequently lowering blood pressure.
Pharmacokinetics
Onset
30-60 minutes
Excretion
Primarily excreted via urine (60%) and feces (40%).
Half life
6-8 hours
Absorption
Rapidly absorbed from the gastrointestinal tract; bioavailability approximately 60-70%.
Metabolism
Extensively metabolized in the liver via CYP450 enzymes.
Side Effects
Contraindications
- Hypersensitivity to the hypothetical active ingredient or any excipients.
- Severe hypotension.
- Cardiogenic shock.
- Pregnancy and lactation (consider risks vs benefits).
Drug Interactions
NSAIDs
May reduce the antihypertensive effect; monitor blood pressure.
Diuretics
May potentiate the hypotensive effect, leading to excessive blood pressure drop.
Other Antihypertensives
Additive hypotensive effects; monitor blood pressure closely.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include severe hypotension, dizziness, and tachycardia. Treatment involves symptomatic and supportive care, including intravenous fluids and vasopressors if necessary. Hemodialysis is not likely to be effective.
Pregnancy & Lactation
Not recommended during pregnancy, especially during the second and third trimesters, due to potential fetal harm. Avoid during breastfeeding, as the active ingredient may pass into breast milk.
Side Effects
Contraindications
- Hypersensitivity to the hypothetical active ingredient or any excipients.
- Severe hypotension.
- Cardiogenic shock.
- Pregnancy and lactation (consider risks vs benefits).
Drug Interactions
NSAIDs
May reduce the antihypertensive effect; monitor blood pressure.
Diuretics
May potentiate the hypotensive effect, leading to excessive blood pressure drop.
Other Antihypertensives
Additive hypotensive effects; monitor blood pressure closely.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include severe hypotension, dizziness, and tachycardia. Treatment involves symptomatic and supportive care, including intravenous fluids and vasopressors if necessary. Hemodialysis is not likely to be effective.
Pregnancy & Lactation
Not recommended during pregnancy, especially during the second and third trimesters, due to potential fetal harm. Avoid during breastfeeding, as the active ingredient may pass into breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Pharmacies nationwide
Approval Status
Approved (Hypothetical)
Patent Status
Patent expired (Hypothetical)
Clinical Trials
Hypothetical clinical trials demonstrated significant reduction in systolic and diastolic blood pressure compared to placebo in patients with essential hypertension.
Lab Monitoring
- Blood pressure monitoring
- Renal function tests (serum creatinine, BUN)
- Electrolyte levels (especially potassium)
Doctor Notes
- Emphasize adherence to therapy and lifestyle modifications.
- Monitor blood pressure regularly and adjust dose as needed.
- Counsel patients on potential dizziness and orthostatic hypotension.
Patient Guidelines
- Take regularly as prescribed, even if you feel well.
- Do not stop the medication suddenly without consulting your doctor.
- Report any unusual side effects to your doctor.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to compensate.
Driving Precautions
This medication may cause dizziness or fatigue, especially at the start of treatment. Use caution when driving or operating machinery until you know how it affects you.
Lifestyle Advice
- Maintain a healthy diet low in sodium and saturated fats.
- Engage in regular physical activity.
- Avoid excessive alcohol consumption and smoking.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.