Sastid
Generic Name
Salicylic Acid & Sulfur
Manufacturer
Stiefel (part of GSK)
Country
USA
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sastid 100 mg medicated bar | ৳ 358.92 | N/A |
Description
Overview of the medicine
Sastid is a medicated cleanser containing salicylic acid and sulfur, used for treating acne and oily skin. It helps to exfoliate the skin and reduce oiliness.
Uses & Indications
Dosage
Adults
Apply to wet skin, lather well, leave on for 1-2 minutes, then rinse thoroughly. Use 1-2 times daily or as directed by a physician.
Elderly
Same as adult dosage. No specific adjustment required.
Renal_impairment
No specific dosage adjustment needed for topical use.
How to Take
For external use only. Wet the affected skin area, apply the cleanser, gently massage to create lather, leave on for 1-2 minutes, then rinse thoroughly with water. Avoid contact with eyes.
Mechanism of Action
Salicylic acid acts as a keratolytic, helping to shed dead skin cells and unclog pores, thus preventing comedone formation. Sulfur has antibacterial, antifungal, and keratolytic properties; it inhibits bacterial growth (especially P. acnes) and reduces oil production.
Pharmacokinetics
Onset
Noticeable improvement in skin condition typically within several days to a few weeks of consistent use.
Excretion
Systemic excretion is negligible due to limited absorption.
Half life
Not clinically significant due to minimal systemic absorption and rapid local metabolism.
Absorption
Minimal systemic absorption when applied topically; primarily acts on the skin surface. Some absorption can occur through damaged skin.
Metabolism
Primarily metabolized locally in the skin to inactive metabolites.
Side Effects
Contraindications
- Known hypersensitivity to salicylic acid, sulfur, or any other component of the formulation.
- On broken, irritated, or severely inflamed skin.
- In children under 2 years of age.
Drug Interactions
Other topical acne medications
Using with other topical acne treatments (e.g., retinoids, benzoyl peroxide) may lead to excessive dryness, peeling, or irritation. Consult a doctor.
Topical preparations with similar keratolytic effects
Concomitant use with other topical exfoliating agents or harsh cleansers may increase skin irritation or dryness. Use with caution.
Storage
Store at room temperature (below 30°C), away from direct sunlight and excessive heat or moisture. Do not freeze.
Overdose
Topical overdose may cause increased local irritation, redness, dryness, and peeling. Discontinue use and wash the affected area thoroughly with water. If irritation persists, seek medical advice. Systemic toxicity is rare with topical application.
Pregnancy & Lactation
Consult a doctor before use, especially if pregnant or breastfeeding. While systemic absorption is low, caution is advised.
Side Effects
Contraindications
- Known hypersensitivity to salicylic acid, sulfur, or any other component of the formulation.
- On broken, irritated, or severely inflamed skin.
- In children under 2 years of age.
Drug Interactions
Other topical acne medications
Using with other topical acne treatments (e.g., retinoids, benzoyl peroxide) may lead to excessive dryness, peeling, or irritation. Consult a doctor.
Topical preparations with similar keratolytic effects
Concomitant use with other topical exfoliating agents or harsh cleansers may increase skin irritation or dryness. Use with caution.
Storage
Store at room temperature (below 30°C), away from direct sunlight and excessive heat or moisture. Do not freeze.
Overdose
Topical overdose may cause increased local irritation, redness, dryness, and peeling. Discontinue use and wash the affected area thoroughly with water. If irritation persists, seek medical advice. Systemic toxicity is rare with topical application.
Pregnancy & Lactation
Consult a doctor before use, especially if pregnant or breastfeeding. While systemic absorption is low, caution is advised.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Usually 2-3 years from the manufacturing date, check specific packaging for details.
Availability
Pharmacies, supermarkets
Approval Status
Approved
Patent Status
No longer patented
Clinical Trials
The active ingredients, salicylic acid and sulfur, are well-established and have been studied extensively for their efficacy in treating acne and other dermatological conditions. Sastid, as a combination product, leverages these known effects.
Doctor Notes
- Educate patients on the proper application technique to minimize irritation and maximize efficacy.
- Advise patients that mild dryness or peeling is common initially, but if severe, they should reduce frequency or discontinue.
- Stress the importance of sun protection due to increased photosensitivity with salicylic acid use.
- Not for use on broken or very sensitive skin.
Patient Guidelines
- Use exactly as directed by your doctor or as per the product label.
- Avoid contact with eyes, mouth, and other mucous membranes. If contact occurs, rinse thoroughly with water.
- If excessive skin irritation, redness, or peeling develops, reduce frequency of use or discontinue and consult a healthcare professional.
- Keep out of reach of children.
Missed Dose Advice
If a dose is missed, simply apply the next scheduled dose. Do not apply a double dose to compensate for the missed one.
Driving Precautions
Sastid is a topical product and is not expected to affect driving ability or operate machinery.
Lifestyle Advice
- Maintain good skin hygiene and cleanse regularly.
- Avoid harsh scrubbing or abrasive cleansers that can further irritate acne-prone skin.
- Use non-comedogenic (pore-clogging) skincare and makeup products.
- Protect skin from sun exposure, as salicylic acid can increase sun sensitivity. Use sunscreen.
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