Scabin
Generic Name
Benzyl Benzoate 25% w/v Emulsion
Manufacturer
ACI Limited
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| scabin 25 w emulsion | ৳ 12.55 | N/A |
Description
Overview of the medicine
Scabin-25-w-emulsion contains Benzyl Benzoate 25% w/v, used for the topical treatment of scabies and pediculosis.
Uses & Indications
Dosage
Adults
Apply a thin layer over the entire body from the neck down, avoiding the face and scalp. Leave on for 24 hours, then wash off. Repeat application after 7 days if necessary.
Elderly
Same as adult dosage, but use with caution due to thinner skin.
Renal_impairment
No specific dose adjustment required for topical application.
How to Take
For external use only. Apply to clean, dry skin. Avoid contact with eyes, mouth, and mucous membranes. Wash hands thoroughly after application. For children, dilute 1 part emulsion with 1 part water before application.
Mechanism of Action
Benzyl Benzoate acts as a neurotoxin on arthropods, causing excitation and subsequent paralysis and death of the mites and lice. It also has a solvent action on the chitinous exoskeleton of the mites.
Pharmacokinetics
Onset
Effects typically observed within hours of application.
Excretion
Mainly through urine as metabolites if systemically absorbed.
Half life
Not well established for topical application; primarily acts locally.
Absorption
Minimal systemic absorption through intact skin. Significant absorption may occur through damaged skin.
Metabolism
Rapidly hydrolyzed to benzoic acid and benzyl alcohol if absorbed systemically, then conjugated and excreted.
Side Effects
Contraindications
- Known hypersensitivity to Benzyl Benzoate or any components of the emulsion
- Acute eczema or broken skin (risk of increased systemic absorption and irritation)
- Children under 2 years of age (use with extreme caution and only if diluted)
Drug Interactions
Storage
Store below 30°C. Protect from light. Do not freeze.
Overdose
Accidental ingestion may cause nausea, vomiting, stomach cramps, and central nervous system depression. Excessive topical application may lead to skin irritation or systemic effects from absorption. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation when used as directed, but consultation with a physician is recommended. Minimal systemic absorption is expected.
Side Effects
Contraindications
- Known hypersensitivity to Benzyl Benzoate or any components of the emulsion
- Acute eczema or broken skin (risk of increased systemic absorption and irritation)
- Children under 2 years of age (use with extreme caution and only if diluted)
Drug Interactions
Storage
Store below 30°C. Protect from light. Do not freeze.
Overdose
Accidental ingestion may cause nausea, vomiting, stomach cramps, and central nervous system depression. Excessive topical application may lead to skin irritation or systemic effects from absorption. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation when used as directed, but consultation with a physician is recommended. Minimal systemic absorption is expected.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years, refer to product label.
Availability
Pharmacies
Approval Status
Approved by regulatory bodies
Patent Status
Generic
WHO Essential Medicine
YesClinical Trials
Benzyl Benzoate has been widely used for decades. Modern clinical trials specifically for 'Scabin-25-w-emulsion' might be limited, but its efficacy is well-established.
Lab Monitoring
- No routine lab monitoring required for topical use.
Doctor Notes
- Advise patients on proper application technique and environmental decontamination.
- Counsel on potential skin irritation and how to manage it.
- Emphasize treatment of all household members simultaneously.
Patient Guidelines
- Ensure all family members and close contacts are treated simultaneously to prevent re-infestation.
- Wash all clothing, bedding, and towels used by the infested person in hot water.
- Vacuum carpets and upholstered furniture and discard the vacuum bag.
Missed Dose Advice
Since it's a single or two-application treatment, if an application is missed or prematurely washed off, reapply as soon as remembered, following the full course.
Driving Precautions
Does not affect ability to drive or operate machinery.
Lifestyle Advice
- Maintain good personal hygiene.
- Avoid sharing personal items like clothing and towels.
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