Scarin
Generic Name
Dimethicone 5% w/w Topical Cream
Manufacturer
PharmaCorp Health
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| scarin 5 w cream | ৳ 30.00 | N/A |
Description
Overview of the medicine
Scarin-5-w-cream is a topical cream formulated with 5% w/w Dimethicone, designed to improve the appearance of old and new scars. It helps to soften, flatten, and smooth scars, while also reducing discoloration and itching. It works by creating a protective barrier over the scar, promoting a balanced healing environment.
Uses & Indications
Dosage
Adults
Apply a thin layer of Scarin-5-w-cream to the affected scar area 2-3 times daily. Gently massage until fully absorbed. For best results, use for a minimum of 3 months.
Elderly
No specific dosage adjustment required. Use as per adult dosage.
Renal_impairment
No specific dosage adjustment required as systemic absorption is minimal.
How to Take
Ensure the scar area is clean and dry before application. Apply a small amount of cream and gently massage it into the scar until it is fully absorbed. Allow the cream to dry completely before covering with clothing or makeup.
Mechanism of Action
Dimethicone, a type of silicone, forms an occlusive, breathable layer over the scar. This layer helps to hydrate the scar tissue, regulate collagen production, and reduce trans-epidermal water loss. By creating an optimal environment, it helps to flatten, soften, and reduce the redness and itching associated with scars. It is believed to normalize the production of fibroblasts and collagen, preventing hypertrophic and keloid scar formation.
Pharmacokinetics
Onset
Improvements typically noticeable within 3-4 weeks, with optimal results after 3-6 months of consistent use.
Excretion
Mainly removed by washing from the skin surface; minimal to no systemic excretion.
Half life
Not applicable for topical, non-systemically absorbed agents.
Absorption
Minimal systemic absorption after topical application to intact skin. Primarily acts on the skin surface.
Metabolism
Not significantly metabolized systemically.
Side Effects
Contraindications
- Known hypersensitivity to Dimethicone or any other ingredient in the cream.
- Should not be applied to open wounds or unhealed skin.
- Avoid contact with mucous membranes (eyes, nose, mouth) or internally.
Drug Interactions
Other topical agents
Avoid simultaneous application with other topical medications on the same area unless advised by a healthcare professional, as it may reduce the effectiveness of either product.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Overdose is highly unlikely with topical application. In case of accidental ingestion, seek medical advice. If excessive cream is applied topically, simply wipe off the excess.
Pregnancy & Lactation
While topical dimethicone is generally considered safe due to minimal systemic absorption, it is advisable to consult a healthcare professional before use during pregnancy or breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Pharmacies, drugstores
Approval Status
Approved
Patent Status
Generic available
Clinical Trials
Clinical studies have shown that silicone-based creams like Scarin-5-w-cream significantly improve scar appearance by reducing height, redness, and discomfort in both hypertrophic and keloid scars. Efficacy is generally observed with consistent use over several months.
Lab Monitoring
- No specific laboratory monitoring is required for topical Scarin-5-w-cream.
Doctor Notes
- Counsel patients on the importance of consistent application for optimal results.
- Emphasize that scar improvement is a gradual process and patience is key.
- Advise against applying to open wounds to prevent infection and delayed healing.
Patient Guidelines
- Use consistently for several months for best results.
- Apply only to closed, healed scars. Do not use on open wounds.
- Protect treated scar area from direct sunlight.
- If irritation occurs, discontinue use and consult a doctor.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. Do not apply a double dose to make up for a missed one. Continue with your regular application schedule.
Driving Precautions
Scarin-5-w-cream is for topical use and has no known effects on the ability to drive or operate machinery.
Lifestyle Advice
- Maintain good skin hygiene around the scar area.
- Avoid harsh scrubbing or scratching of the scar.
- Stay hydrated and maintain a balanced diet for overall skin health.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.