Sectil
Generic Name
Sectil 40 mg Capsule
Manufacturer
Incepta Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sectil 40 mg capsule | ৳ 7.00 | ৳ 70.00 |
Description
Overview of the medicine
Sectil 40 mg Capsule contains Secnidazole, an antiprotozoal and antibacterial agent, used for the treatment of various parasitic and bacterial infections.
Uses & Indications
Dosage
Adults
Dosage must be determined by a physician based on the specific infection and patient's condition. Standard Secnidazole dosages are typically much higher (e.g., 500 mg, 1 g, 2 g) than 40 mg.
Elderly
No specific dosage adjustment for elderly patients is generally required, but caution is advised. Consult a physician.
Renal_impairment
Dosage adjustment may be necessary in patients with severe renal impairment. Consult a physician.
How to Take
Take the capsule orally, preferably with food to minimize gastrointestinal discomfort. Swallow whole with water.
Mechanism of Action
Secnidazole works by interfering with the DNA synthesis of susceptible microorganisms, leading to their death. It exhibits bactericidal action against anaerobic bacteria and parasiticidal action against protozoa.
Pharmacokinetics
Onset
Varies by indication and individual response.
Excretion
Mainly excreted via urine, with a significant portion eliminated unchanged.
Half life
Approximately 17-29 hours, indicating a prolonged duration of action.
Absorption
Well absorbed orally, with peak plasma concentrations achieved within 3-4 hours.
Metabolism
Primarily metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to Secnidazole or other nitroimidazole derivatives.
- First trimester of pregnancy.
Drug Interactions
Alcohol
Disulfiram-like reaction (nausea, vomiting, abdominal cramps, flushing) may occur. Avoid alcohol consumption during and for at least 72 hours after treatment.
Lithium
May increase lithium plasma levels, leading to toxicity.
Warfarin (anticoagulants)
May potentiate the anticoagulant effect of warfarin, increasing the risk of bleeding. Close monitoring of INR is recommended.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment should be administered. There is no specific antidote for Secnidazole.
Pregnancy & Lactation
Generally contraindicated in the first trimester of pregnancy. Use with caution in the second and third trimesters only if clearly needed and the potential benefits outweigh the risks. Secnidazole is excreted in breast milk; therefore, use during lactation should be avoided or breast-feeding interrupted.
Side Effects
Contraindications
- Hypersensitivity to Secnidazole or other nitroimidazole derivatives.
- First trimester of pregnancy.
Drug Interactions
Alcohol
Disulfiram-like reaction (nausea, vomiting, abdominal cramps, flushing) may occur. Avoid alcohol consumption during and for at least 72 hours after treatment.
Lithium
May increase lithium plasma levels, leading to toxicity.
Warfarin (anticoagulants)
May potentiate the anticoagulant effect of warfarin, increasing the risk of bleeding. Close monitoring of INR is recommended.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment should be administered. There is no specific antidote for Secnidazole.
Pregnancy & Lactation
Generally contraindicated in the first trimester of pregnancy. Use with caution in the second and third trimesters only if clearly needed and the potential benefits outweigh the risks. Secnidazole is excreted in breast milk; therefore, use during lactation should be avoided or breast-feeding interrupted.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years from the date of manufacture, depending on storage conditions.
Availability
Available in pharmacies
Approval Status
Approved (Generic)
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Secnidazole is a well-established drug, and extensive clinical trials have confirmed its efficacy and safety for approved indications. Ongoing research may explore new applications or formulations.
Lab Monitoring
- Liver function tests may be monitored in patients receiving prolonged treatment.
- Complete blood count (CBC) may be advised for long-term therapy.
Doctor Notes
- Emphasize the importance of patient compliance with the full treatment course to prevent recurrence and resistance.
- Advise patients on the strong interaction with alcohol and the need for strict avoidance.
- Educate patients on potential side effects and when to seek medical attention.
Patient Guidelines
- Complete the full course of treatment as prescribed by your doctor, even if your symptoms improve.
- Avoid alcohol consumption during and for at least 72 hours after treatment.
- Do not exceed the recommended dose.
- Inform your doctor about any unusual symptoms or side effects.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Sectil 40 mg Capsule may cause dizziness or drowsiness in some individuals. Exercise caution when driving or operating machinery until you know how the medicine affects you.
Lifestyle Advice
- Maintain good personal hygiene to prevent reinfection, especially for parasitic infections.
- Drink plenty of fluids to prevent dehydration, especially if experiencing diarrhea.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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