Selcaxen
Generic Name
selcaxen-40-mg-capsule
Manufacturer
MediPharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| selcaxen 40 mg capsule | ৳ 1,350.00 | N/A |
Description
Overview of the medicine
Selcaxen 40 mg Capsule is a proton pump inhibitor used to reduce stomach acid production. It treats conditions like GERD, ulcers, and Zollinger-Ellison syndrome.
Uses & Indications
Dosage
Adults
Typical dose is 20-40 mg once daily, preferably before breakfast. For severe conditions, up to 80 mg daily may be prescribed.
Elderly
No specific dose adjustment required for elderly patients, but caution is advised.
Renal_impairment
No dose adjustment required for renal impairment.
How to Take
Swallow the capsule whole with water before a meal, usually in the morning. Do not chew or crush.
Mechanism of Action
Irreversibly binds to and inhibits the H+/K+-ATPase (proton pump) in gastric parietal cells, blocking the final step of acid secretion.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Primarily excreted in urine (80%) and feces (20%).
Half life
1-1.5 hours
Absorption
Rapidly absorbed after oral administration, bioavailability is approximately 40%.
Metabolism
Extensively metabolized in the liver via CYP2C19 and CYP3A4.
Side Effects
Contraindications
- Hypersensitivity to selcaxen or any component of the formulation
- Concomitant use with nelfinavir
Drug Interactions
Digoxin
Increased digoxin absorption and levels
Warfarin
Increased INR/bleeding risk
Clopidogrel
Reduced antiplatelet effect (CYP2C19 interaction)
Methotrexate
Increased methotrexate levels
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include drowsiness, tachycardia, nausea, headache. Treatment is symptomatic and supportive; no specific antidote.
Pregnancy & Lactation
Use during pregnancy only if clearly needed. Consult a doctor. Limited data on excretion in breast milk; use with caution during lactation.
Side Effects
Contraindications
- Hypersensitivity to selcaxen or any component of the formulation
- Concomitant use with nelfinavir
Drug Interactions
Digoxin
Increased digoxin absorption and levels
Warfarin
Increased INR/bleeding risk
Clopidogrel
Reduced antiplatelet effect (CYP2C19 interaction)
Methotrexate
Increased methotrexate levels
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include drowsiness, tachycardia, nausea, headache. Treatment is symptomatic and supportive; no specific antidote.
Pregnancy & Lactation
Use during pregnancy only if clearly needed. Consult a doctor. Limited data on excretion in breast milk; use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, hospitals, clinics
Approval Status
DGDA approved
Patent Status
Patent expired
WHO Essential Medicine
YesClinical Trials
Phase III clinical trials demonstrated efficacy in healing erosive esophagitis in 8-12 weeks. Post-marketing surveillance continues to monitor long-term safety.
Lab Monitoring
- Magnesium levels (long-term use)
- Vitamin B12 levels (long-term use)
- Liver function tests
Doctor Notes
- Consider lowest effective dose for shortest duration.
- Counsel patients on potential long-term risks.
- Review need for continued PPI therapy periodically.
Patient Guidelines
- Take as directed by your doctor.
- Do not stop taking without consulting your doctor.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. If it's almost time for the next dose, skip the missed dose and resume your regular schedule. Do not double dose.
Driving Precautions
Selcaxen may cause dizziness in some individuals. If affected, avoid driving or operating machinery.
Lifestyle Advice
- Avoid spicy and fatty foods.
- Eat smaller, more frequent meals.
- Elevate the head of your bed if you have GERD.
- Avoid smoking and excessive alcohol consumption.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.