Simplovir
Generic Name
Antiviralum 200 mg Tablet
Manufacturer
MediCorp Pharmaceuticals
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| simplovir 200 mg tablet | ৳ 14.00 | ৳ 140.00 |
Description
Overview of the medicine
Simplovir 200 mg Tablet is an antiviral medication used to treat certain viral infections by inhibiting viral replication. It is typically prescribed for short-term treatment courses.
Uses & Indications
Dosage
Adults
200 mg twice daily for 5-7 days, depending on the infection.
Elderly
No specific dose adjustment required, but monitor renal function.
Renal_impairment
Dose adjustment required for creatinine clearance < 50 mL/min.
How to Take
Take orally with or without food. Swallow the tablet whole with water. Do not crush or chew.
Mechanism of Action
Simplovir acts as a direct-acting antiviral by interfering with the viral RNA polymerase, thereby preventing the replication of viral genetic material and the assembly of new viral particles within host cells.
Pharmacokinetics
Onset
Clinical effects observed within 24-48 hours of initiation.
Excretion
Mainly excreted through urine as metabolites, with a small portion excreted unchanged.
Half life
Approximately 8-12 hours.
Absorption
Rapidly absorbed after oral administration, with peak plasma concentrations reached within 1-2 hours.
Metabolism
Primarily metabolized in the liver via cytochrome P450 enzymes.
Side Effects
Contraindications
- Hypersensitivity to the active substance or any excipients
- Severe hepatic impairment
Drug Interactions
Ritonavir
Concurrent use may increase Simplovir plasma concentrations, requiring dose adjustment.
Carbamazepine
May decrease Simplovir efficacy due to enzyme induction.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
No specific antidote. Management involves supportive care and symptomatic treatment. Hemodialysis may be considered in severe cases.
Pregnancy & Lactation
Use in pregnancy only if potential benefit outweighs potential risk to the fetus. Consult a doctor before use during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Under patent
Clinical Trials
Multiple Phase III clinical trials demonstrated significant efficacy and safety profile against target viral infections.
Lab Monitoring
- Liver function tests (LFTs)
- Renal function (Creatinine, GFR)
Doctor Notes
- Advise patients on adherence to full course.
- Monitor for signs of hepatic dysfunction, especially in patients with pre-existing liver conditions.
Patient Guidelines
- Complete the full course of medication, even if symptoms improve.
- Do not share this medication with others.
- Store at room temperature away from moisture and heat.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness in some individuals; exercise caution when driving or operating machinery.
Lifestyle Advice
- Maintain good hydration during treatment.
- Avoid alcohol consumption while on medication.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.