Siodil Rejuvi Cream
Generic Name
Retinol, Hyaluronic Acid, Niacinamide Cream
Manufacturer
DermiCare Pharmaceuticals
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| siodil rejuvi cream cream | ৳ 1,590.00 | N/A |
Description
Overview of the medicine
Siodil Rejuvi Cream is a multi-action dermatological cream formulated to reduce the appearance of fine lines and wrinkles, improve skin texture, and provide intense hydration. It combines the benefits of Retinol for cellular renewal, Hyaluronic Acid for deep moisture, and Niacinamide for strengthening the skin barrier and reducing inflammation.
Uses & Indications
Dosage
Adults
Apply a thin layer to a clean, dry face and neck once daily, preferably at night. Start with 2-3 times per week and gradually increase frequency.
Elderly
Same as adults, with caution for increased skin sensitivity.
Renal_impairment
No dosage adjustment needed for topical application.
How to Take
For external use only. Apply to the skin after cleansing. Avoid contact with eyes and mucous membranes.
Mechanism of Action
Retinol promotes cell turnover and stimulates collagen production, reducing wrinkles. Hyaluronic Acid attracts and retains moisture in the skin, plumping it up. Niacinamide improves skin barrier function, reduces redness and inflammation, and minimizes pore appearance.
Pharmacokinetics
Onset
Visible improvements in skin texture and hydration within 2-4 weeks; fine lines and wrinkles may take 8-12 weeks.
Excretion
Not significant systemic excretion for topical use.
Half life
Not applicable for local topical action with minimal systemic absorption.
Absorption
Minimal systemic absorption expected for topical application; primarily acts locally on the skin.
Metabolism
Topical retinoids are metabolized locally in the skin to active forms; Niacinamide is converted to NAD/NADH. Hyaluronic Acid is degraded by hyaluronidases locally.
Side Effects
Contraindications
- Hypersensitivity to any component of the cream
- Severe eczema or broken skin in the application area
Drug Interactions
Topical Benzoyl Peroxide
May inactivate Retinol. Apply at different times of the day (e.g., Benzoyl Peroxide in the morning, Siodil Rejuvi Cream at night).
Other strong topical exfoliants (e.g., salicylic acid, glycolic acid)
May increase irritation and dryness. Use with caution or on alternate days.
Storage
Store below 30°C in a cool, dry place. Protect from direct sunlight and excessive heat. Keep out of reach of children.
Overdose
Overuse or excessive application may lead to increased skin irritation, redness, peeling, and dryness. Discontinue use and apply a soothing moisturizer. Seek medical advice if irritation persists.
Pregnancy & Lactation
Retinol use in pregnancy is generally not recommended due to potential risks. Consult a physician before use during pregnancy or lactation. Hyaluronic Acid and Niacinamide are generally considered safe topically but physician consultation is advised.
Side Effects
Contraindications
- Hypersensitivity to any component of the cream
- Severe eczema or broken skin in the application area
Drug Interactions
Topical Benzoyl Peroxide
May inactivate Retinol. Apply at different times of the day (e.g., Benzoyl Peroxide in the morning, Siodil Rejuvi Cream at night).
Other strong topical exfoliants (e.g., salicylic acid, glycolic acid)
May increase irritation and dryness. Use with caution or on alternate days.
Storage
Store below 30°C in a cool, dry place. Protect from direct sunlight and excessive heat. Keep out of reach of children.
Overdose
Overuse or excessive application may lead to increased skin irritation, redness, peeling, and dryness. Discontinue use and apply a soothing moisturizer. Seek medical advice if irritation persists.
Pregnancy & Lactation
Retinol use in pregnancy is generally not recommended due to potential risks. Consult a physician before use during pregnancy or lactation. Hyaluronic Acid and Niacinamide are generally considered safe topically but physician consultation is advised.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date (unopened). 6 months after opening.
Availability
Pharmacies, beauty stores, online retailers
Approval Status
Approved as a cosmetic/OTC dermatological product
Patent Status
Proprietary formulation, specific blend may be patented
Clinical Trials
Clinical studies showed significant reduction in fine lines and wrinkles, and improved skin hydration and elasticity over 8-12 weeks of use.
Lab Monitoring
- No specific lab monitoring required for topical cosmetic use.
Doctor Notes
- Advise patients to start slowly with Retinol products to minimize irritation.
- Emphasize daily broad-spectrum SPF protection due to increased sun sensitivity.
- Educate on potential 'retinization' period (initial dryness/peeling) which usually resolves with continued use.
Patient Guidelines
- Apply to clean, dry skin.
- Use sunscreen daily as Retinol can increase sun sensitivity.
- Avoid direct contact with eyes, lips, and mucous membranes.
- Do not use on broken or irritated skin.
- Introduce gradually to allow skin to adapt.
Missed Dose Advice
If a dose is missed, apply it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.
Driving Precautions
No known effects on driving ability.
Lifestyle Advice
- Maintain a consistent skincare routine.
- Stay hydrated by drinking plenty of water.
- Protect skin from excessive sun exposure.
- Eat a balanced diet rich in antioxidants.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.