Sleepwel
Generic Name
Melatonin 2 mg Tablet
Manufacturer
Generic Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sleepwel 2 mg tablet | ৳ 3.02 | ৳ 30.19 |
Description
Overview of the medicine
Sleepwel 2 mg Tablet contains Melatonin, a hormone naturally produced in the body that helps regulate sleep-wake cycles. It is used to treat various sleep disorders, promoting a more natural and restorative sleep.
Uses & Indications
Dosage
Adults
2 mg once daily, 1-2 hours before bedtime.
Elderly
No specific dose adjustment is usually required, but caution is advised. Same as adults or lower dose may be considered.
Renal_impairment
No specific dose adjustment is generally needed, but caution and medical supervision are recommended in severe cases.
How to Take
Take the tablet orally, with or without food, 1-2 hours before the intended bedtime. Do not crush or chew the tablet if it is an extended-release formulation.
Mechanism of Action
Melatonin acts on MT1 and MT2 receptors in the suprachiasmatic nucleus (SCN) of the brain, which are involved in controlling circadian rhythms and promoting sleep.
Pharmacokinetics
Onset
Within 30-60 minutes.
Excretion
Excreted primarily via urine as metabolites.
Half life
Approximately 0.5-2 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract; significant first-pass metabolism.
Metabolism
Primarily hepatic, mainly by CYP1A2 and CYP1A1 to 6-hydroxymelatonin and its sulfate and glucuronide conjugates.
Side Effects
Contraindications
- Hypersensitivity to melatonin or any excipients of the tablet
- Severe liver or kidney impairment (use with caution)
Drug Interactions
Warfarin
May enhance anticoagulant effect; monitor INR.
Nifedipine
May decrease the efficacy of melatonin.
Fluvoxamine
May increase melatonin levels due to CYP1A2 inhibition, leading to increased sedation.
CNS Depressants (e.g., alcohol, benzodiazepines)
May enhance sedative effects.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overdose is generally well-tolerated. Symptoms may include prolonged drowsiness, dizziness, or headache. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Not recommended during pregnancy or lactation due to insufficient data. Consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to melatonin or any excipients of the tablet
- Severe liver or kidney impairment (use with caution)
Drug Interactions
Warfarin
May enhance anticoagulant effect; monitor INR.
Nifedipine
May decrease the efficacy of melatonin.
Fluvoxamine
May increase melatonin levels due to CYP1A2 inhibition, leading to increased sedation.
CNS Depressants (e.g., alcohol, benzodiazepines)
May enhance sedative effects.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overdose is generally well-tolerated. Symptoms may include prolonged drowsiness, dizziness, or headache. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Not recommended during pregnancy or lactation due to insufficient data. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Pharmacies, hospitals
Approval Status
Approved
Patent Status
Patent Expired
Clinical Trials
Clinical trials have demonstrated the efficacy of melatonin in reducing sleep latency and improving sleep quality in patients with insomnia and other sleep disorders.
Lab Monitoring
- Generally, no routine lab monitoring is required for melatonin.
Doctor Notes
- Assess underlying causes of insomnia before prescribing.
- Advise patients on proper sleep hygiene practices.
- Monitor for signs of excessive sedation or other adverse effects.
Patient Guidelines
- Take the tablet at the same time each night, preferably 1-2 hours before bedtime.
- Avoid alcohol consumption while taking this medicine.
- Do not drive or operate machinery after taking Sleepwel, as it may cause drowsiness.
- Consult your doctor if your sleep problems persist after regular use.
Missed Dose Advice
If a dose is missed, do not take a double dose to make up for it. Take the next scheduled dose at the usual time. If it is already close to your next dose, skip the missed dose.
Driving Precautions
This medicine may cause drowsiness. Avoid driving or operating heavy machinery until you know how it affects you.
Lifestyle Advice
- Maintain good sleep hygiene (e.g., consistent bedtime, dark and quiet room).
- Limit screen time before bed.
- Avoid caffeine and heavy meals late in the evening.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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