Starbac
Generic Name
starbac
Manufacturer
MediCorp Pharma Ltd.
Country
Bangladesh
Loading images...
Description
Overview of the medicine
Starbac (generic name: starbac) is a broad-spectrum fluoroquinolone antibiotic used to treat a variety of bacterial infections.
Uses & Indications
Dosage
Adults
500 mg once daily for 7-14 days, depending on the infection.
Elderly
No dose adjustment required based solely on age; renal function should be considered.
Renal_impairment
Reduced dosage recommended for creatinine clearance < 50 mL/min.
How to Take
Can be taken with or without food. Ensure adequate hydration. Do not take with antacids containing magnesium or aluminum, or with iron supplements.
Mechanism of Action
Starbac inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. This leads to bacterial cell death.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Mainly via the kidneys, largely as unchanged drug.
Half life
Approximately 6-8 hours
Absorption
Rapidly and almost completely absorbed after oral administration, with peak plasma concentrations achieved within 1-2 hours.
Metabolism
Minimally metabolized in the liver; primarily excreted unchanged.
Side Effects
Contraindications
- Hypersensitivity to starbac or other fluoroquinolones
- History of tendinitis or tendon rupture associated with fluoroquinolone use
- Myasthenia gravis
Drug Interactions
NSAIDs
Increased risk of CNS stimulation and seizures.
Warfarin
May enhance anticoagulant effects, requiring INR monitoring.
Corticosteroids
Increased risk of tendon rupture.
Antacids/Iron Supplements
Reduced absorption of starbac.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms include CNS effects (confusion, dizziness, seizures), gastrointestinal reactions. Treatment is symptomatic and supportive; hemodialysis is not effective.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs risk. Excreted in breast milk; avoid use during lactation due to potential risks to infant.
Side Effects
Contraindications
- Hypersensitivity to starbac or other fluoroquinolones
- History of tendinitis or tendon rupture associated with fluoroquinolone use
- Myasthenia gravis
Drug Interactions
NSAIDs
Increased risk of CNS stimulation and seizures.
Warfarin
May enhance anticoagulant effects, requiring INR monitoring.
Corticosteroids
Increased risk of tendon rupture.
Antacids/Iron Supplements
Reduced absorption of starbac.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms include CNS effects (confusion, dizziness, seizures), gastrointestinal reactions. Treatment is symptomatic and supportive; hemodialysis is not effective.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs risk. Excreted in breast milk; avoid use during lactation due to potential risks to infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Extensive phase I, II, and III clinical trials demonstrated efficacy and safety in various bacterial infections.
Lab Monitoring
- Renal function tests (for patients with impaired kidney function)
- INR (if co-administered with warfarin)
- ECG (in patients at risk for QT prolongation)
Doctor Notes
- Counsel patients on potential severe side effects like tendon rupture and neurological adverse reactions.
- Consider alternative antibiotics for uncomplicated infections where possible to preserve fluoroquinolones for more serious indications.
- Monitor renal function, especially in elderly patients.
Patient Guidelines
- Complete the full course of treatment even if symptoms improve.
- Stay well-hydrated.
- Avoid excessive sun exposure due to photosensitivity risk.
- Report any tendon pain, swelling, or inflammation immediately.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose.
Driving Precautions
May cause dizziness or lightheadedness; avoid driving or operating machinery until you know how this medicine affects you.
Lifestyle Advice
- Maintain good hygiene to prevent reinfection.
- Discuss with your doctor before resuming strenuous physical activity if you experienced tendon issues.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Starbac Brand
Other medicines available under the same brand name
